S-Sulfo-DL-cysteine-[2,3,3-d3]

S-Sulfo-DL-cysteine-[2,3,3-d3] is an isotopically labeled compound commonly used in bioscience and analytical applications. Here are some key applications of S-Sulfo-DL-cysteine-[2,3,3-d3]:

Metabolomic Studies: S-Sulfo-DL-cysteine-[2,3,3-d3] is extensively used in metabolomics to trace and quantify sulfur-containing metabolites. The deuterium label allows for precise tracking using mass spectrometry, providing insights into metabolic pathways and fluxes. This aids researchers in understanding diseases such as cancer and metabolic disorders.

Protein Labeling: In proteomics, S-Sulfo-DL-cysteine-[2,3,3-d3] is used to label proteins for mass spectrometry analysis. The isotopic label facilitates the identification and quantification of peptides, enhancing the study of protein expression, modifications, and interactions. This application is crucial for biomarker discovery and understanding cellular functions.

Stable Isotope Dilution Assays: S-Sulfo-DL-cysteine-[2,3,3-d3] helps in stable isotope dilution assays (SIDAs) to quantify sulfur-containing amino acids in complex mixtures. By providing a reliable internal standard, it ensures accurate and reproducible measurements in biological and environmental samples. This technique enhances the precision of analytical results in various research fields.

Pharmacokinetic Studies: This labeled compound is instrumental in pharmacokinetic studies to evaluate the absorption, distribution, metabolism, and excretion (ADME) of drugs containing cysteine. By tracking the labeled sulfur, researchers can gain detailed insights into the drug’s behavior in the body. This information is vital for optimizing drug formulations and improving therapeutic efficacy.