Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009101 |
Molecular Formula: [13C]3H8Cl[15N]O2 |
Molecular Weight: 129.53 |
Chemical Structure |
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Description | Sarcosine-[13C3,15N] HCl is a labelled salt of Sarcosine. Sarcosine is an intermediate of choline metabolism. |
Synonyms | N-methylglycine-13C3,15N HCl |
Related CAS | 637-96-7 (unlabelled) |
Purity | 98% by HPLC; 99% atom 13C, 98% atom 15N |
Sarcosine-[13C3,15N] HCl, a stable isotope-labeled compound, finds diverse applications in bioscience. Here are the key applications:
Metabolomics: Serving as an internal standard in metabolomics studies, Sarcosine-[13C3,15N] HCl facilitates precise quantification of sarcosine levels in biological samples. By introducing this labeled compound into samples, researchers can adjust for variations in sample preparation and instrument responses. This meticulous approach enhances the accuracy and precision of metabolomic analyses, enabling in-depth exploration of metabolic pathways and identification of disease biomarkers.
Cancer Research: Delving into the realm of cancer research, Sarcosine-[13C3,15N] HCl emerges as a crucial tool for investigating sarcosine metabolism and its implications in cancer progression, particularly in prostate cancer. Researchers leverage this labeled sarcosine to track its absorption and transformation within cellular pathways. This insightful approach sheds light on the metabolic shifts linked to cancer and contributes to the formulation of targeted therapeutic strategies.
Protein Structure Elucidation: Stepping into the domain of protein studies, Sarcosine-[13C3,15N] HCl plays a pivotal role in NMR spectroscopy and mass spectrometry for unraveling protein structures and dynamics. By integrating this labeled compound into protein samples, scientists acquire intricate details on protein folding, interactions, and conformational changes. This profound understanding of protein function aids in the design of drugs targeting specific protein structures, fueling advancements in therapeutic approaches.
Nutritional Studies: In the realm of nutritional exploration, Sarcosine-[13C3,15N] HCl serves as a cornerstone for investigating amino acid metabolism and the nutritional status of organisms. Researchers trace the metabolic destiny of sarcosine and scrutinize its impacts on health and diseases. This wealth of knowledge contributes to the development of tailored nutritional interventions and enhances our understanding of the roles amino acids play in human physiology, paving the way for informed dietary strategies.
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