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Simeprevir-[13C,d3]

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General Information
Catalog: BLP-013542
Molecular Formula: C37[13C]H44D3N5O7S2
Molecular Weight: 753.95

Chemical Structure

Description	Simeprevir-[13C,d3] is an isotope analogue of Simeprevir. Simeprevir plays an important role in HCV replication. Data from phase I and II clinical trials of TMC-435350 (TMC 435350; TMC 435; TMC-435350) to date have shown that this agent is well tolerated as a once-daily oral therapy and provides potent antiviral activity in HCV genotype 1-infected subjects, with restoration of liver enzymes and no evidence of viral breakthrough.
Synonyms	TMC435-13Cd3
Related CAS	923604-59-5 (unlabelled)