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Sulfamonomethoxine-[d3]

General Information
Catalog: BLP-013918
Molecular Formula: C11H9D3N4O3S
Molecular Weight: 283.32
Chemical Structure
Sulfamonomethoxine-[d3]
Description An isotope labelled of Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent.
Synonyms N1-(6-Methoxy-4-pyrimidinyl)sulfanilide; 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfomide; 4-Sulfanilamido-6-methoxypyrimidine
Related CAS 1220-83-3 (unlabelled)
Melting Point 204-206°C
Purity 98% by HPLC; 99% atom D;
Appearance White to Off-white Solid

Sulfamonomethoxine-[d3], a deuterated antibiotic compound renowned for its application in research, plays a pivotal role in diverse scientific endeavors. Here are the key applications of Sulfamonomethoxine-[d3]:

Pharmacokinetic Studies: Delving into drug dynamics, Sulfamonomethoxine-[d3] is harnessed in pharmacokinetic studies to meticulously track the absorption, distribution, metabolism, and excretion (ADME) of pharmaceuticals. Its deuterated composition enables precise mass spectrometry analysis, facilitating an in-depth understanding of drug behavior within biological systems. This critical information aids in fine-tuning dosage regimens and enhancing therapeutic effectiveness, shaping the future of pharmaceutical optimization.

Metabolite Identification: In the realm of drug development, Sulfamonomethoxine-[d3] emerges as a key player in the identification and quantification of metabolites originating from primary drugs. Its isotopically labeled form serves as a beacon during mass spectrometry analysis, distinguishing parent drugs from their metabolites with unmatched clarity. This distinction is paramount for unraveling metabolic pathways and predicting potential side effects of newly developed drugs, illuminating the path for safer and more efficacious pharmaceutical interventions.

Environmental Monitoring: Embarking on a quest for environmental safeguarding, Sulfamonomethoxine-[d3] stands as an invaluable tool for assessing contamination levels by sulfonamide antibiotics in natural ecosystems. Serving as an internal standard, its application in environmental studies enables precise quantification of minute traces of antibiotics in water, soil, and biological samples. This surveillance effort plays a critical role in monitoring the ecological impact of pharmaceutical pollutants, safeguarding delicate ecosystems from potential harm.

Bioavailability Studies: At the forefront of pharmaceutical research, Sulfamonomethoxine-[d3] finds its niche in bioavailability studies, shedding light on the fraction of a drug that successfully enters systemic circulation post-administration. Its deuterated essence aids in differentiating it from endogenous compounds, offering a more accurate depiction of drug absorption rates. This precise data serves as a cornerstone for crafting potent drug formulations that maximize therapeutic benefits, heralding a new era of tailored pharmaceutical solutions.

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