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Tafamidis-[d3]

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General Information
Catalog: BLP-014826
Molecular Formula: C14H4D3Cl2NO3
Molecular Weight: 311.13

Chemical Structure

Ordering Information

Catalog Number	Size	Price	Stock	Quantity
BLP-014826	10 mg	$5990	In stock

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Description	Tafamidis-[d3] is deuterium labelled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, showing comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis.
Synonyms	Tafamidis-d3; d3-Tafamidis
IUPAC Name	4,5,7-trideuterio-2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
Related CAS	594839-88-0 (unlabelled)
Canonical SMILES	C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
InChI	InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)/i1D,2D,5D
InChI Key	TXEIIPDJKFWEEC-FYFKOAPZSA-N
Appearance	Crystalline Solid
Storage	-20°C