Name: Tandospirone-[d8]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-004527

CAS: 1794835-73-6

Molecular Formula: C21H21D8N5O2

Molecular Weight: 391.54

Chemical Structure

Description	Isotopic labelled Tandospirone is a potent and selective 5-HT1A receptor partial agonist with Ki of 27 nM. It significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. It also decreased the number of premature responses in a dose-dependent manner. It is used as an antidepressant.
Synonyms	(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (3aa,4ß,7ß,7aa)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (1R,2S,6R,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl](1,1,2,2,3,3,4,4-D8)butyl}-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
IUPAC Name	(1S,2R,6S,7R)-4-[1,1,2,2,3,3,4,4-octadeuterio-4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Related CAS	87760-53-0 (unlabelled)
Canonical SMILES	C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5
InChI	InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-/i1D2,2D2,8D2,9D2
InChI Key	CEIJFEGBUDEYSX-MLALYRAXSA-N
Purity	>98%