Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-004527 |
CAS: 1794835-73-6 |
Molecular Formula: C21H21D8N5O2 |
Molecular Weight: 391.54 |
Chemical Structure |
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Description | Isotopic labelled Tandospirone is a potent and selective 5-HT1A receptor partial agonist with Ki of 27 nM. It significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. It also decreased the number of premature responses in a dose-dependent manner. It is used as an antidepressant. |
Synonyms | (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (3aa,4ß,7ß,7aa)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (1R,2S,6R,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl](1,1,2,2,3,3,4,4-D8)butyl}-4-azatricyclo[5.2.1.02,6]decane-3,5-dione |
IUPAC Name | (1S,2R,6S,7R)-4-[1,1,2,2,3,3,4,4-octadeuterio-4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione |
Related CAS | 87760-53-0 (unlabelled) |
Canonical SMILES | C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5 |
InChI | InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-/i1D2,2D2,8D2,9D2 |
InChI Key | CEIJFEGBUDEYSX-MLALYRAXSA-N |
Purity | >98% |
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