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Tavaborole-[d2]

General Information
Catalog: BLP-004550
Molecular Formula: C7H4D2BFO2
Molecular Weight: 153.95
Chemical Structure
Tavaborole-[d2]
Description Labelled Tavaborole. Tavaborole (AN2690) is a potent antifungal that targets the post-transfer editing site of leucyl-tRNA synthetase (LeuRS). Tavaborole forms a covalent adduct with the 3' adenosine of tRNA(leu) at the editing site of fungal, but not bacterial LeuRS, locking the enzyme in an inactive conformation. Tavaborole was recently approved for the treatment of onychomycosis of the toenail in adults.
IUPAC Name 3,3-dideuterio-5-fluoro-1-hydroxy-2,1-benzoxaborole
Related CAS 174671-46-6 (unlabelled)
Canonical SMILES B1(C2=C(CO1)C=C(C=C2)F)O
InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2/i4D2
InChI Key LFQDNHWZDQTITF-APZFVMQVSA-N
Purity ≥90%
Solubility Soluble in Methanol
Appearance White to Off-white Solid
Storage Store at 2-8°C

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