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Tetrahydro uridine-[d3]

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General Information
Catalog: BLP-004605
Molecular Formula: C9H13D3N2O6
Molecular Weight: 251.25

Chemical Structure

Description	Labelled Tetrahydro uridine. Tetrahydrouridine, a derivative of Uridine, is a potent and reversible competitive inhibitor of cytidine deaminase (CDD) (Ki = 54 and 240 nM for human and E. coli enzymes, respectively). Tetrahydrouridine has the potential to treat tumors with highly expressed CDA as it inhibits cell proliferation through cell cycle regulation despite of cytidine deaminase expression levels deaminase (CDA). Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.
Related CAS	18771-50-1 (unlabelled)
Purity	≥95%
Solubility	Soluble in DMSO
Appearance	White to Off-white Powder
Storage	Store at 2-8°C