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Application Area
Environmental
Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic
Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry
Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research
Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Thiothixene-[d8]

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General Information
Catalog: BLP-007429
Molecular Formula: C23H21D8N3O2S2
Molecular Weight: 451.67
Chemical Structure
Thiothixene-[d8]
Description Labelled Thiothixene. Thiothixene is a thioxanthene derivative and a dopamine antagonist with antipsychotic property. It is used in the treatment of psychoses like schizophrenia. It blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thus decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects. It blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. It possesses weak affinity for the histamine H1 and alpha-adrenergic receptors.
Synonyms N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide-d8 (7CI,8CI); N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide-d8; 2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene-d8; CP 12252-1-d8; N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide-d8; NSC 108165-d8; Navan-d8; Navane-d8; Navaron-d8; Orbinamon-d8; P 4657B-d8; Thixit-d8; Tiotixene-d8
Related CAS 3313-26-6 (unlabelled)
Purity >98%
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