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Thiothixene-[d8]

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Thiothixene-[d8]

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General Information
Catalog: BLP-007429
Molecular Formula: C23H21D8N3O2S2
Molecular Weight: 451.67

Chemical Structure

Description	Labelled Thiothixene. Thiothixene is a thioxanthene derivative and a dopamine antagonist with antipsychotic property. It is used in the treatment of psychoses like schizophrenia. It blocks postsynaptic dopamine receptors in the mesolimbic system and medullary chemoreceptor trigger zone, thus decreasing dopamine activity leading to decreased stimulation of the vomiting center and psychotic effects. It blocks the D2 somatodendritic autoreceptor, thereby increasing dopamine turnover. It possesses weak affinity for the histamine H1 and alpha-adrenergic receptors.
Synonyms	N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide-d8 (7CI,8CI); N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide-d8; 2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene-d8; CP 12252-1-d8; N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide-d8; NSC 108165-d8; Navan-d8; Navane-d8; Navaron-d8; Orbinamon-d8; P 4657B-d8; Thixit-d8; Tiotixene-d8
Related CAS	3313-26-6 (unlabelled)
Purity	>98%

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