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Tivozanib-[13C4,15N]

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General Information
Catalog: BLP-000867
Molecular Formula: C18[13C]4H19ClN3[15N]O5
Molecular Weight: 459.83

Chemical Structure

Description	Tivozanib-[13C4,15N] is the labelled analogue of Tivozanib. Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death.
Synonyms	[13C4,15N]-Tivozanib
IUPAC Name	1-(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-3-(5-(methyl-13C)isoxazol-3-yl-3,4,5-13C3-2-15N)urea
Related CAS	475108-18-0 (unlabelled)
Purity	95%
Appearance	Beige to White Solid