About Us Careers Contact Us

Inquiry List

* Name:
* Phone:
* Service & Products of Interested: [Nitrogen-15] Tivozanib-[13C4,15N]
Project Description:
* Quantity
* Email:
* Organization We recommend you to leave us your work email address so that we can serve you better. Please leave your organization information here if you don't have a work email address.
* Verification Code:

Our Highlights

Optimal Prices
Buying products on this site guarantees the best price
Flexible Batches
Flexible batch size to meet different needs of global customers
Prompt Delivery
Warehouses in multiple cities to ensure timely delivery
Quality Assurance
Strict process parameter control to ensure product quality
One-to-one Customization
One-to-one custom synthesis for special structural needs

Application Area

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Clinical diagnostic

In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.

Organic Chemistry

Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.

Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Tivozanib-[13C4,15N]

Inquiry

General Information
Catalog: BLP-000867
Molecular Formula: C18[13C]4H19ClN3[15N]O5
Molecular Weight: 459.83

Chemical Structure

Description	Tivozanib-[13C4,15N] is the labelled analogue of Tivozanib. Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death.
Synonyms	[13C4,15N]-Tivozanib
IUPAC Name	1-(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-3-(5-(methyl-13C)isoxazol-3-yl-3,4,5-13C3-2-15N)urea
Related CAS	475108-18-0 (unlabelled)
Purity	95%
Appearance	Beige to White Solid