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Trametinib-[d4]

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General Information
Catalog: BLP-008160
Molecular Formula: C26H19D4FIN5O4
Molecular Weight: 619.42

Chemical Structure

Description	One of the isotopic labelled form of Trametinib, which has been found to be an EGFR kinase inhibitor and could be used against advanced cutaneous melanoma.
Synonyms	N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide-d4; G 02442104-d4; GSK 1120212-d4; JTP 74057-d4
IUPAC Name	N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]-2,4,5,6-tetradeuteriophenyl]acetamide
Related CAS	871700-17-3 (unlabelled)
Canonical SMILES	CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5
InChI	InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)/i4D,5D,6D,12D
InChI Key	LIRYPHYGHXZJBZ-PUYVGKOOSA-N
Purity	>98%