Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-007499 |
Molecular Formula: C6H10D4O8S2 |
Molecular Weight: 282.30 |
Chemical Structure |
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Description | Labelled Treosulfan. Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological conditions, treosulfan converts nonenzymatically to L-diepoxybutane via a monoepoxide intermediate. The monoepoxide intermediate and L-diepoxybutane alkylate DNA at guanine residues and produce DNA interstrand crosslinks, resulting in DNA fragmentation and apoptosis. In escalated doses, this agent also exhbits myeloablative and immunosuppressive activities. |
IUPAC Name | [(2S,3S)-1,1,4,4-tetradeuterio-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate |
Related CAS | 299-75-2 (unlabelled) |
Canonical SMILES | CS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O |
InChI | InChI=1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1/i3D2,4D2 |
InChI Key | YCPOZVAOBBQLRI-OGDJEXPBSA-N |
Solubility | Soluble in DMSO, Chloroform |
Appearance | White to Off-white Solid |
Storage | Store at 2-8°C |
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