α,β-trehalose-[UL-13C12] - Isotope / BOC Sciences

General Information
Catalog: BLP-012707
Molecular Formula: [13C]12H22O11
Molecular Weight: 354.20

General Information

Catalog: BLP-012707

Molecular Formula: [13C]12H22O11

Molecular Weight: 354.20

Chemical Structure

Description	α,β-trehalose-[UL-13C12] is the labelled analogue of α,β-trehalose, which is one of the prevalent olligosaccharides found in honey.
Synonyms	alpha,beta-[UL-13C12]trehalose; [UL-13C6]Glc(a1-1b)[UL-13C6]Glc; alpha,beta-trehalose-U-13C12; α,β-[UL-13C12]trehalose; 1-O-α-D-[UL-13C6]glucopyranosyl-β-D-[UL-13C6]glucopyranoside; Neotrehalose-13C12; β-D-Glucopyranosyl α-D-glucopyranoside-13C12; α-D-[UL-13C6]Glcp-(1↔1)-β-D-[UL-13C6]Glcp
IUPAC Name	(2R,3S,4S,5R,6R)-2-(hydroxy(1-13C)methyl)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxy(1-13C)methyl)(2,3,4,5,6-13C5)oxan-2-yl]oxy(2,3,4,5,6-13C5)oxane-3,4,5-triol
Related CAS	585-91-1 (unlabelled)
Melting Point	>160°C (dec.)
Purity	98%
Solubility	Soluble in Methanol (Slightly), Water (Slightly)
Appearance	White to Off-white Solid
Storage	Store at 2-8°C

α,β-Trehalose-[UL-13C12] is a stable isotope-labeled compound of trehalose utilized in diverse scientific contexts. Here are the key applications of α,β-trehalose-[UL-13C12]:

Metabolic Flux Analysis: In the realm of metabolic research, α,β-trehalose-[UL-13C12] serves as an invaluable tracer for probing metabolic pathways and fluxes. By monitoring the incorporation of labeled trehalose into metabolic intermediates, researchers unlock insights into carbohydrate metabolism, shedding light on cellular energy regulation and the intricate role of trehalose in stress responses.

Cellular Stress Studies: Delving into the protective role of trehalose in cellular resilience against varied stressors like dehydration and freezing, α,β-trehalose-[UL-13C12] emerges as a pivotal tool. Observing the fate and distribution of labeled trehalose offers a window into its efficacy as a shield. These insights drive advancements in preservation techniques for biological samples and therapeutic innovations, unveiling novel avenues for scientific exploration.

Proteomics Research: Navigating the complexities of proteomics, α,β-trehalose-[UL-13C12] emerges as a key player in unraveling protein-trehalose interactions and their impact on protein stability and functionality. Leveraging isotopic labeling for precise signal detection in mass spectrometry, researchers delve into the realm of trehalose-bound proteins, crucial for understanding protein folding diseases and engineering strategies for protein stabilization.

Glycomics Studies: At the intersection of glycomics and cellular processes, α,β-trehalose-[UL-13C12] takes center stage in unraveling the dynamics of glycosylation and its implications on cellular dynamics. Through the integration of labeled trehalose into glycan structures, researchers scrutinize the influence of trehalose on glycoprotein function and stability. This exploration is pivotal for deciphering the role of glycosylation in health and disease, paving the path for potential therapeutic breakthroughs and enhanced understanding of cellular mechanisms.