Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-000304 |
Molecular Formula: [13C]12H22O11 |
Molecular Weight: 354.21 |
Chemical Structure |
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Synonyms | alpha,alpha-[UL-13C12]trehalose; [UL-13C6]Glc(a1-1a)[UL-13C6]Glc; alpha,alpha-trehalose-U-13C12; α,α-[UL-13C12]trehalose; 1-O-α-D-[UL-13C6]Glucopyranosyl-α-D-[UL-13C6]glucopyranoside; α-D-[UL-13C6]Glcp-(1↔1)-α-D-[UL-13C6]Glcp; D-(+)-Trehalose-13C12; α-D-Glucopyranosyl-α-D-glucopyranoside-13C12; D-Trehalose-13C12; α,α−Trehalose-13C12 |
IUPAC Name | (2R,3S,4S,5R,6R)-2-(hydroxy(1-13C)methyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxy(1-13C)methyl)(2,3,4,5,6-13C5)oxan-2-yl]oxy(2,3,4,5,6-13C5)oxane-3,4,5-triol |
Related CAS | 99-20-7 (unlabelled) |
Canonical SMILES | C(C1C(C(C(C(O1)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O |
InChI | InChI=1S/C12H22O11/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12/h3-20H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1,11+1,12+1 |
InChI Key | HDTRYLNUVZCQOY-OSKVYJSUSA-N |
Purity | 99% by CP; 99% atom 13C |
Solubility | Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
Appearance | White to Off-white Solid |
Storage | Store at 2-8°C |
D-Trehalose-[13C12], a stable isotope-labeled form of trehalose, has a variety of applications in bioscience and industry. Here are some key applications of D-Trehalose-[13C12]:
Metabolic Tracing Studies: D-Trehalose-[13C12] is utilized in metabolic tracing studies to understand trehalose metabolism and its role in cellular processes. By tracking the incorporation of the labeled carbon atoms, researchers can map out metabolic pathways and fluxes. This helps in elucidating the metabolic fate and dynamics of trehalose in different organisms.
Proteomics and Structural Biology: In proteomics, D-Trehalose-[13C12] can be used to stabilize proteins and protect them from denaturation during mass spectrometry analysis. Trehalose's stabilizing properties extend the detectable range of proteins and improve the quality of structural data. This application is particularly valuable in studying protein folding interactions and stability.
Agricultural Biotechnology: D-Trehalose-[13C12] can aid in the investigation of stress responses in plants. By applying labeled trehalose, researchers can study the role of trehalose in drought and salinity tolerance. This knowledge can be used to develop crops with enhanced resilience to environmental stresses, contributing to sustainable agriculture practices.
Food and Beverage Industry: D-Trehalose-[13C12] serves as a marker to trace and ensure the authenticity of food products. In the production and quality control processes, the labeled trehalose can be detected to confirm product consistency and origin. This application is important for maintaining product quality and preventing fraud in the food supply chain.
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