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[UL-13C6gal]Lactose Monohydrate

General Information
Catalog: BLP-013245
Molecular Formula: C6[13C]6H24O12
Molecular Weight: 366.27
Chemical Structure
[UL-13C6gal]Lactose Monohydrate
Description [UL-13C6gal]Lactose Monohydrate is the labelled analogue of D-Lactose Monohydrate, which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets.
Synonyms [1',2',3',4',5',6'-13C6]lactose monohydrate; 4-O-beta-D-[UL-13C6]galactopyranosyl-D-glucose; lactose-1',2',3',4',5',6'-13C6 monohydrate
Related CAS 64044-51-5 (unlabelled)
Melting Point 205-207°C
Solubility Soluble in Methanol, Water
Appearance White to Off-White Solid

[UL-13C6gal]Lactose Monohydrate, an isotopically labeled lactose molecule, has a range of applications in research and industry. Here are the key applications:

Metabolic Pathway Tracing: In metabolic studies, [UL-13C6gal]Lactose Monohydrate is crucial for tracing the complex pathways of lactose metabolism in organisms. By incorporating this labeled lactose into experimental systems, researchers can meticulously track and quantify how lactose is processed, utilizing advanced mass spectrometry techniques. This approach provides valuable insights into lactose digestion mechanisms and helps to uncover the interplay between lactose metabolism and related metabolic disorders.

Enzyme Activity Assays: In enzymology, this labeled lactose molecule is used to investigate the activity and kinetics of enzymes like lactase and other glycosidases. By using [UL-13C6gal]Lactose Monohydrate, scientists can accurately measure how efficiently these enzymes hydrolyze lactose, which is critical for understanding enzyme functionality and developing treatments for lactose intolerance. This analytical method provides a detailed view of enzyme performance and helps in optimizing therapeutic interventions.

Microbial Ecology: In microbial ecology, [UL-13C6gal]Lactose Monohydrate is a powerful tool for exploring dairy fermentation processes and microbial interactions. By introducing this isotopically labeled lactose into fermentation experiments, researchers can use stable isotope probing to track how different microbial species assimilate lactose. This application enhances our understanding of microbial dynamics in dairy fermentation, optimizes production processes, and provides insights into probiotic efficacy and the interactions within microbial communities.

Pharmaceutical Research: In the pharmaceutical industry, [UL-13C6gal]Lactose Monohydrate is used to study the behavior of lactose-based excipients in drug formulations. Researchers can assess the safety, absorption, and metabolic pathways of this labeled lactose within the human body. This analysis is crucial for ensuring that pharmaceutical products containing lactose are biocompatible and effective, thereby supporting the development of safe and efficient drug delivery systems.

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