Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-006977 |
Molecular Formula: C12H10D14O12 |
Molecular Weight: 374.40 |
Chemical Structure |
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Synonyms | [UL-2H14]maltose monohydrate; 4-O-alpha-D-[UL-2H7]glucopyranosyl-D-[UL-2H7]glucose |
IUPAC Name | (3R,4R,5R,6S)-6-(hydroxymethyl-d2)-5-(((2R,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl-d2)tetrahydro-2H-pyran-2-yl-2,3,4,5,6-d5)oxy)tetrahydro-2H-pyran-2,3,4,5,6-d5-2,3,4-triol hydrate |
Related CAS | 6363-53-7 (unlabelled) |
Solubility | Soluble in Methanol, Water |
Appearance | White to Off-white Solid |
Storage | Store at -20°C |
Maltose-[d14] monohydrate, a stable isotope-labeled compound frequently used in scientific research, finds diverse applications in metabolic studies, structural biology, enzymology, and pharmacokinetics. Here are the key applications:
Metabolic Tracing: Maltose-[d14] monohydrate serves as a vital tool in metabolic tracing investigations, shedding light on carbohydrate metabolism across varied biological systems. By monitoring the incorporation of deuterium-labeled maltose into metabolic pathways, researchers glean insights into energy utilization and metabolic flux. This application stands at the forefront of unraveling metabolic disorders and enhancing the efficiency of biotechnological processes.
Structural Biology: Within the realm of structural biology, maltose-[d14] monohydrate emerges as a key player for scrutinizing the structure and dynamics of carbohydrate-binding proteins. The use of isotope labeling enhances contrast in nuclear magnetic resonance (NMR) and mass spectrometry analyses, allowing researchers to delve into conformational changes and binding interactions crucial for the proteins' functionality. This sophisticated approach aids in dissecting the intricate world of protein structures and functions.
Enzymology: In the domain of enzymology, maltose-[d14] monohydrate stands as an indispensable resource for exploring the enzymatic conversion of maltose in diverse biochemical reactions. Through the incorporation of labeled maltose in enzyme assays, scientists can meticulously track reaction rates and mechanisms via isotopic shifts. This meticulous investigation plays a pivotal role in characterizing enzyme functionality and fostering the development of enzyme-centric industrial applications, paving the way for innovative biochemical advancements.
Pharmacokinetics: Maltose-[d14] monohydrate emerges as a cornerstone in pharmacokinetic inquiries, illuminating the absorption, distribution, metabolism, and excretion (ADME) dynamics of carbohydrate-based pharmaceuticals. Leveraging deuterium labeling, researchers attain precise insights into the compound's journey within biological systems. This knowledge proves instrumental in refining and optimizing the efficacy of carbohydrate-based therapeutics, steering the way towards enhanced drug development and delivery strategies.
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