UR-144 N-5-Hydroxypentyl metabolite-[indole-d5]

General Information
Catalog: BLP-009113
Molecular Formula: C21H24D5NO2
Molecular Weight: 332.49

General Information

Catalog: BLP-009113

Molecular Formula: C21H24D5NO2

Molecular Weight: 332.49

Chemical Structure

Description	An isotope labelled metabolite of UR-144. UR-144 is a potent synthetic cannabinoid.
Synonyms	[1-(5-hydroxypentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone-2,4,5,6,7-d5; XLR11 N-(5-hydroxypentyl) metabolite-d5
IUPAC Name	[2,4,5,6,7-pentadeuterio-1-(5-hydroxypentyl)indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone
Related CAS	895155-95-0 (unlabelled)
Canonical SMILES	CC1(C(C1(C)C)C(=O)C2=CN(C3=CC=CC=C32)CCCCCO)C
InChI	InChI=1S/C21H29NO2/c1-20(2)19(21(20,3)4)18(24)16-14-22(12-8-5-9-13-23)17-11-7-6-10-15(16)17/h6-7,10-11,14,19,23H,5,8-9,12-13H2,1-4H3/i6D,7D,10D,11D,14D
InChI Key	AFWBYMXUEMOBRP-OAWGXGCBSA-N
Purity	98% by HPLC; 98% atom D
Storage	Store at -20°C

UR-144 N-5-Hydroxypentyl metabolite-[indole-d5], a stable isotopic labeled compound, finds diverse applications notably in analytical and forensic toxicology. Here are the key applications:

Analytical Standards: Serving as an internal standard, UR-144 N-5-Hydroxypentyl metabolite-[indole-d5] plays a pivotal role in quantitatively analyzing synthetic cannabinoids in biological samples. Its isotopic labeling facilitates precise measurement and calibration of analytical instruments like LC-MS/MS, ensuring accurate substance detection in forensic toxicology and clinical research settings.

Forensic Toxicology: Empowering forensic scientists, this compound aids in identifying and quantifying synthetic cannabinoid metabolites in biological specimens. By utilizing UR-144 N-5-Hydroxypentyl metabolite-[indole-d5] as a reference standard, they can trace parent compounds and their metabolites in urine, blood, or hair samples. This capability is essential for drug monitoring, legal inquiries, and comprehending the pharmacokinetics of synthetic cannabinoids, with a keen focus on forensic implications.

Metabolite Profiling: Researchers leverage UR-144 N-5-Hydroxypentyl metabolite-[indole-d5] to delve into the metabolic pathways of synthetic cannabinoids. By monitoring the labeled metabolite, scientists can elucidate how these compounds undergo processing and detoxification in the body, shedding light on metabolism and potential toxicological impacts on human health in a manner rich with depth and intricacy.

Pharmacokinetic Studies: In the realm of pharmacokinetic research, UR-144 N-5-Hydroxypentyl metabolite-[indole-d5] acts as a crucial tool for decoding the absorption, distribution, metabolism, and excretion (ADME) of synthetic cannabinoids. By scrutinizing the pharmacokinetics of this labeled metabolite, researchers can glean insights into the in vivo behavior of these substances, a critical step in shaping safe clinical applications and regulatory frameworks with profound implications for public health and safety.