| Description |
Valsartan-[d9] is the labelled analogue of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. |
| Synonyms |
Valsartan D9; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine-d9 |
| IUPAC Name |
(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid |
| Related CAS |
137862-53-4 (unlabelled)
|
| Isomeric SMILES |
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O |
| Canonical SMILES |
CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O |
| InChI |
InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i1D3,4D2,5D2,10D2 |
| InChI Key |
ACWBQPMHZXGDFX-KDDXQTGLSA-N |
| Boiling Point |
684.9±0.0 °C at 760 mmHg |
| Melting Point |
>92°C (dec.) |
| Purity |
98% HPLC |
| Density |
1.2±0.0 g/cm3 |
| Solubility |
Soluble in Methanol |
| Appearance |
White to Off-white Solid |
| Application |
An isotopic labelled form of Valsartan, an antagonist of nonpeptide angiotensin II AT1-receptor, is commonly used as an antihypertensive agent and seems to have potential effect in Alzheimer's disease. |
| Shelf Life |
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
| Storage |
Store at -20°C |
![Valsartan-[d9]](https://resource.bocsci.com/structure/1089736-73-1.gif)
