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Vemurafenib-[d5]

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Vemurafenib-[d5]

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General Information
Catalog: BLP-007584
CAS: 1365986-90-8
Molecular Formula: C23H13D5ClF2N3O3S
Molecular Weight: 494.95

Chemical Structure

Description	Vemurafenib is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity than wild-type B-Raf.
Synonyms	N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide-d5; PLX 4032-d5; RG 7204-d5; Ro 51-85426-d5
Related CAS	918504-65-1 (unlabelled)