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Venlafaxine-[d6]

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Venlafaxine-[d6]

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General Information
Catalog: BLP-007589
CAS: 940297-06-3
Molecular Formula: C17H21D6NO2
Molecular Weight: 283.44

Chemical Structure

Description	Labelled Venlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases.
Synonyms	1-(2-(bis(methyl-d3)amino)-1-(4-methoxyphenyl)ethyl)cyclohexan-1-ol
IUPAC Name	1-[2-[bis(trideuteriomethyl)amino]-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
Related CAS	93413-69-5 (unlabelled) 1062606-12-5 (hydrochloride)
Canonical SMILES	CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O
InChI	InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3/i1D3,2D3
InChI Key	PNVNVHUZROJLTJ-WFGJKAKNSA-N
Purity	≥90%
Solubility	Soluble in DMSO
Appearance	White to Off-white Solid
Storage	Store at 2-8°C

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