Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-007638 |
CAS: 325484-33-1 |
Molecular Formula: C9[13C]H10D3N5O4 |
Molecular Weight: 271.25 |
Chemical Structure |
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Description | Labelled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo. |
Synonyms | 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione-13CD3 |
IUPAC Name | 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-(trideuterio(1-13C)methyl)pyrimidine-2,4-dione |
Related CAS | 30516-87-1 (unlabelled) |
Canonical SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] |
InChI | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1/i1+1D3 |
InChI Key | HBOMLICNUCNMMY-JOUPVGMFSA-N |
Purity | ≥90% |
Solubility | Soluble in DMSO, in Chloroform |
Appearance | Pale Yellow Hygroscopic Solid |
Storage | Store at 2-8°C |
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