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Zidovudine-[d4]

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Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

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Metabolic Research

Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.

Environmental

Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

Zidovudine-[d4]

Name: Zidovudine-[d4]
Brand: BOC Sciences
Rating: 5 (1 reviews)

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General Information
Catalog: BLP-007639
Molecular Formula: C10H9D4N5O4
Molecular Weight: 271.27

Chemical Structure

Description	Labelled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo.
Synonyms	1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione-6-d
IUPAC Name	1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-6-deuterio-5-(trideuteriomethyl)pyrimidine-2,4-dione
Related CAS	30516-87-1 (unlabelled)
Canonical SMILES	CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
InChI	InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1/i1D3,3D
InChI Key	HBOMLICNUCNMMY-BTDYSWPSSA-N
Purity	>98%
Solubility	Soluble in DMSO, Methanol
Appearance	Off-white Powder
Storage	Store at -20°C