Product List

The nitrogen serves as an essential element of life and is found in a variety of isotopic forms, each with its unique process and applicability. More recently, 15N (nitrogen 15) has become a subject of great interest due to its rarity and entirely distinct chemistry. High quality and durable nitrogen 15 labeled peptide, amino acid, nucleotide, steroid, API, impurity, inhibitor, metabolite, carbohydrate, polymer, fatty acid and lipid products from BOC Sciences. For more types of custom stable isotope services, please feel free to contact us.

Isotopes of Nitrogen

Nitrogen is an important life element that affects the metabolism of organisms and is widely distributed in nature. Nitrogen primarily comprises two stable isotopes: nitrogen-14 (14N) and nitrogen-15 (15N). Nitrogen-14 constitutes the vast majority of natural nitrogen, accounting for approximately 99.6% of the element's abundance. In contrast, nitrogen-15 is relatively rare, making up the remaining 0.4% of natural nitrogen. In addition to stable isotopes, nitrogen has several radioisotopes with varying atomic masses and half-lives. These include nitrogen-13 (13N) and nitrogen-16 (16N), along with other short-lived isotopes. Nitrogen-13, for instance, has a half-life of 9.965 minutes and is produced in the atmosphere through nuclear reactions involving gamma rays and neutrons. Each nitrogen isotope possesses specific nuclear properties, such as spin and decay modes. For example, nitrogen-15 has a fractional nuclear spin of one-half, distinct from the integer spin of nitrogen-14. The resulting difference in spin renders nitrogen-15 unique among the common isotopes and makes it useful in certain types of analysis, such as nuclear magnetic resonance (NMR) spectroscopy.

Isotopes of Nitrogen 15

A nitrogen atom with three extra neutrons is known as nitrogen-15, and it is the only stable nitrogen isotope with a nuclear spin greater than zero. This special feature makes nitrogen-15 very useful for NMR spectroscopy, where its much smaller total line width enables analysis that is more precise and sensitive.

Fractional Nuclear Spin

Nitrogen-15 has a nuclear spin of one-half where nitrogen-14 has an integer spin. Its unique nuclear property renders nitrogen-15 nuclear magnetic resonance (NMR) behaviors highly useful for several analytical applications.

Low Natural Abundance

Nitrogen-15 is not prevalent in comparison to Nitrogen-14. It occurs as a small quantity (0.4%) of natural Nitrogen. This scarcity makes it an interesting isotopic target for use in certain research applications.

Stable Performance

Due to its lack of 14C radioactivity most of the analytical methods applied to the determination of 15N abundances at the atom-related level, have been proven to be of great analytical accuracy of all of the radioisotokens of Nitrogen.

What is Nitrogen-15 Used for?

Nitrogen-15 finds widespread applications across diverse scientific disciplines, owing to its stable performance and low thermal neutron capture cross-section.

NMR Spectroscopy

Nitrogen-15 is extensively utilized in NMR spectroscopy, particularly in biomolecular studies. Its fractional nuclear spin results in narrower line widths compared to nitrogen-14, enhancing the resolution and sensitivity of NMR experiments. This makes nitrogen-15 invaluable for investigating protein structure, dynamics, and interactions in biological systems.

Isotopic Labeling

Nitrogen-15 is commonly employed as a tracer atom in isotopic labeling experiments. By replacing natural nitrogen atoms with nitrogen-15 in molecules such as amino acids, peptides, and nucleic acids, researchers can track the fate and behavior of these compounds in biological systems with precision. This enables studies on metabolic pathways, protein synthesis, and cellular processes, contributing to advancements in fields like biochemistry, pharmacology, and medicine.

Environmental Studies

Nitrogen-15 tracing is utilized in environmental science to investigate nitrogen cycling and pollution dynamics. By analyzing the isotopic composition of nitrogen compounds in ecosystems, researchers can elucidate sources of nitrogen pollution, assess nutrient cycling processes, and monitor environmental impacts. Nitrogen-15 serves as a valuable tool for understanding ecosystem dynamics and informing sustainable resource management practices.

What are Nitrogen-15 Labeled Compounds?

Nitrogen-15 labeled compound refers to using the stable isotope nitrogen-15 instead of the original nitrogen in the compound. Nitrogen-15 is the only applicable tracer in biomedical experiments. Nitrogen-15 labeled amino acids, peptides, carbohydrates, nucleic acids, lipids, steroids, and other compounds are widely used in medicine, life sciences, environmental sciences, agricultural research and other fields.

• Medicine: Nitrogen-15 labeled compounds can be used for studies on metabolic transformation, exploration of metabolic reaction mechanisms, auxiliary clinical diagnosis, monitoring of lesions, clinical nutrition research, etc.
• Life Sciences: Nitrogen-15 labeled compounds can be used in the biosynthesis of natural organic matter, pharmacokinetics research, drug metabolite identification, pharmacological research, etc.
• Environmental science: Nitrogen-15 is a good pollutant indicator. Nitrogen-15 labeled compounds can be used in various researches such as air and water quality.
• Agricultural research: Nitrogen-15 labeled compounds can be used in plant physiology and biochemistry research, soil and plant nutrition research, plant protection research, crop improvement, biological nitrogen fixation, etc.

Benefits of Our Nitrogen 15 Isotopes

With unique strengths in its isotopic products, BOC Sciences is the international market leader for nitrogen-15 (15N) and chosen supplier to countless researchers and industries around the globe. Some of the key benefits of our nitrogen-15 isotopes include:

High Purity and Stability

BOC Sciences ensures the highest standards of purity and stability in our nitrogen-15 isotopes. Our rigorous quality control measures and state-of-the-art production facilities guarantee isotopic products of exceptional purity, free from impurities or contaminants. Researchers can rely on the stability and consistency of our nitrogen-15 isotopes for precise and reliable experimental results.

Versatile Applications

Our nitrogen-15 isotopes find diverse applications across various scientific disciplines, including biochemistry, pharmacology, environmental science, and agriculture. Whether used in NMR spectroscopy, isotopic labeling experiments, environmental tracing, or medical imaging, our nitrogen-15 isotopes deliver unparalleled performance and versatility, enabling groundbreaking research and discoveries.

Custom Solutions

At BOC Sciences, we understand that every research project has unique requirements. That's why we offer customizable solutions to meet the specific needs of our customers. Whether you require nitrogen-15 labeled compounds with specific enrichment levels, chemical modifications, or packaging formats, our experienced team works closely with you to tailor our isotopic products to your exact specifications.

Reliable Supply Chain

With over two decades of experience in the isotopic industry, BOC Sciences has established a robust and reliable supply chain to ensure uninterrupted access to nitrogen-15 isotopes. Our streamlined production processes, extensive inventory, and efficient logistics network guarantee prompt delivery of isotopic products to our customers worldwide. Researchers can trust BOC Sciences to provide consistent and timely access to nitrogen-15 isotopes for their research needs.

FAQ

1. How many neutrons does nitrogen 15 have?

Nitrogen-15 (15N) has 8 neutrons.

2. How many protons does nitrogen 15 have?

Nitrogen-15 (15N) has 7 protons.

3. What is the difference between nitrogen 14 and nitrogen 15?

The main difference between nitrogen-14 (14N) and nitrogen-15 (15N) is their number of neutrons. Nitrogen-14 has seven protons and seven neutrons, while nitrogen-15 has seven protons and eight neutrons. Therefore, nitrogen-15 has one more neutron than nitrogen-14.

4. How many protons neutrons and electrons are in nitrogen 15?

Nitrogen-15 (15N) has seven protons, eight neutrons, and seven electrons.

5. What is the percentage in nature of nitrogen 15?

In nature, the abundance of nitrogen-15 is approximately 0.365%.

6.Is nitrogen-15 natural?

Yes, nitrogen-15 is natural.