Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
In contemporary scientific research, isotope labeled synthesis reagents are indispensable for monitoring molecular processes with a remarkable level of specificity. Most notably, the encapsulation of isotopes — atoms that share a number of protons but differ in neutrons from their family members— into chemical compounds allow researchers to tag materials types for unquantified analyses. BOC Sciences is committed to providing customers with isotope-labeled synthesis reagents. We offer a complete range of labeled synthesis reagents. All products come with comprehensive analytical data files and are of high chemical purity. In addition, we also provide custom isotope labeling service for any synthesis reagents, you can directly provide the synthesis reagents to be labeled or make a request such as the type of labeling isotope, the labeling site, and the isotope enrichment.
Isotope labeled synthesis reagents are chemical compounds that have been modified to include isotopes of elements within their structure. These isotopes serve as tracers or markers, providing valuable information about the behavior and interactions of these compounds in various experimental settings. The incorporation of isotopes can be achieved through chemical synthesis or metabolic processes, allowing for detailed analysis and tracking of labeled substances. Synthesis reagents labeled by isotope mean chemical reagents such as intermediates and raw material monomers labeled by isotopes in the process of reagent synthesis. Stable isotope labeling synthesis reagents could judge the process of biochemical reaction according to the moving position of tracer elements, so as to understand the structure and function of cells, the changes of chemical substances and the reaction mechanism.
BOC Sciences offers a comprehensive suite of isotope labeling services tailored for the synthesis of reagents, designed to meet the high standards of precision and quality required for advanced scientific research. Our services cater to diverse applications, including drug development, metabolic studies, environmental analysis, and proteomics. Leveraging our extensive expertise and state-of-the-art technology, we ensure that our isotope labeling services deliver reliable and accurate results. We utilize advanced techniques to enhance the efficacy and precision of our isotope labeling services:
We offer labeling with stable isotopes such as Carbon-13 (13C), Nitrogen-15 (15N), Oxygen-18 (18O), and Deuterium (2H). Our stable isotope labeling is ideal for long-term studies and detailed analytical applications, including metabolic flux analysis and structural elucidation.
For more types of stable isotope labeling compounds, please check our isotopic product list directly.
BOC Sciences is a 20-year expert in the field of isotope labeling and synthesis. We are dedicated to offering high-tier, individual solutions created by our team of specialists in a scientific and compliant manner.
By using cutting-edge technology and advanced analytical methods, BOC Sciences guarantees the quality of isotope labeling services to our clients. We have state-of-the-art equipment for exact isotope incorporation and accurate measurement in our laboratories.
We offer a wide array of service from custom labelling to state-of-art proteomics research. Our solutions are customized as per the need of every experiment to achieve maximum efficiency.
We strive to continue offering products and services of the utmost quality. Our structured quality control processes and compliance with industry standards ensure that these isotope labeled synthesis reagents are reliable, reproducible in use.
In order to gain information about chemical reactions or biological processes, one of the central techniques used is isotopic labelling - putting stable or radioactive isotopes into molecules that are then tracked through a reaction. The tracking of the isotopes through various stages provides insight into molecular interactions, reaction mechanisms and metabolic pathways.
Products that contain specific isotopes as part of their structure are isotope-labeled compounds. These labels are chemical or physical agents, most of the time stable isotopes ideally non-radioactive ones useful for research and diagnostics. They assist modelling molecular behaviour, metabolic networks and the chemical kinetics.
Isotopic labeling of a molecule does not influence the chemical-reaction chemically reactive behavior but changes some physical properties like mass and nuclear spin. This enables the tracking, and analysis of labeled molecules in different systems with detailed information (metabolomics) at all levels for reactions to molecular mechanisms such as enzymatic or catalytic reaction kinetics and material transformations.
Tracking the metabolism of these labeled molecules by isotopically labeling them to study how they are processed and transformed in biological systems For instance, a labeled glucose can be used to follow its transformation into other metabolites that would allow an evaluation of metabolic pathways or the activity and efficiency of different enzymes involved in those pathways.
By replacing one of reporter no endogenous isotopes (C, H, O or N) present in the final metabolic compound with a stable/ radioactive isotope not naturally existing for this element. This is achieved through chemical synthesis (i.e., the desired isotope has to be built in into compound) or by methods specifically replacing certain atoms with isotopic analogs.
Isotope-labeled chemicals are compounds in which one or more atoms have been replaced with isotopes. These labels, either stable or radioactive, enable researchers to track and analyze the chemical's behavior in various processes, such as metabolism or reaction pathways, by monitoring the isotopic signatures.
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