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Isotope Labeled Synthesis Reagents

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In contemporary scientific research, isotope labeled synthesis reagents are indispensable for monitoring molecular processes with a remarkable level of specificity. Most notably, the encapsulation of isotopes — atoms that share a number of protons but differ in neutrons from their family members— into chemical compounds allow researchers to tag materials types for unquantified analyses. BOC Sciences is committed to providing customers with isotope-labeled synthesis reagents. We offer a complete range of labeled synthesis reagents. All products come with comprehensive analytical data files and are of high chemical purity. In addition, we also provide custom isotope labeling service for any synthesis reagents, you can directly provide the synthesis reagents to be labeled or make a request such as the type of labeling isotope, the labeling site, and the isotope enrichment.

What is Isotope Labeled Synthesis Reagents?

Isotope labeled synthesis reagents are chemical compounds that have been modified to include isotopes of elements within their structure. These isotopes serve as tracers or markers, providing valuable information about the behavior and interactions of these compounds in various experimental settings. The incorporation of isotopes can be achieved through chemical synthesis or metabolic processes, allowing for detailed analysis and tracking of labeled substances. Synthesis reagents labeled by isotope mean chemical reagents such as intermediates and raw material monomers labeled by isotopes in the process of reagent synthesis. Stable isotope labeling synthesis reagents could judge the process of biochemical reaction according to the moving position of tracer elements, so as to understand the structure and function of cells, the changes of chemical substances and the reaction mechanism.

What is Isotope Labeled Synthesis Reagents Used for?

  • Stable isotope labeled synthesis reagents could mark an element and trace its transfer path. For example, labeling synthetic reagent with stable isotope 14C could study the polar transport of auxin and prove that plant auxin can only be transported from the upper end of morphology to the lower end of morphology. The use of stable isotope labeled synthetic reagents has the advantages of simple operation and cheap and easy availability of raw materials.
  • Stable isotope labeled synthesis reagents could mark characteristic elements and explore the role of compounds. With the help of stable isotope tracer technology, the bio-transformation, bio-availability, absorption and retention of synthesis reactions in vivo are studied, so as to reveal the transformation law in vivo.
  • Stable isotope labeled synthesis reagents can explore detailed physiological processes and biological principles. For instance, the secretion process of secretory proteins or the changes of chromosomes during mitosis can be studied by isotope labeling synthesis reagents.
  • Stable isotope labeled synthesis reagents can be customized to synthesize compounds. The synthesis of target compounds using stable isotope labeled synthesis reagents has the advantages of short route, mild conditions, simple operation and high yield. Stable isotope labeled synthesis reagents could prepare products with high isotope abundance, and has the prospect of mass preparation and production

Our Isotope Labeling Services for Synthesis Reagents

BOC Sciences offers a comprehensive suite of isotope labeling services tailored for the synthesis of reagents, designed to meet the high standards of precision and quality required for advanced scientific research. Our services cater to diverse applications, including drug development, metabolic studies, environmental analysis, and proteomics. Leveraging our extensive expertise and state-of-the-art technology, we ensure that our isotope labeling services deliver reliable and accurate results. We utilize advanced techniques to enhance the efficacy and precision of our isotope labeling services:

  • Isotopic Enrichment: We employ high-purity isotopes and advanced enrichment techniques to ensure the optimal incorporation of isotopes into your reagents. This enhances the accuracy of your analyses and the reliability of your data.
  • Multi-Isotope Labeling: For complex studies requiring multiple isotopes, we provide multi-isotope labeling services. This approach allows for simultaneous tracking of different components or processes within your experimental system.
  • Customized Synthesis: We offer tailored synthesis solutions to meet the unique needs of your research. Our facilities are equipped to handle a wide range of synthesis scales and complexities, ensuring that you receive precisely the reagents required for your studies.

Choosing the Type of Stable Isotope Labeling

We offer labeling with stable isotopes such as Carbon-13 (13C), Nitrogen-15 (15N), Oxygen-18 (18O), and Deuterium (2H). Our stable isotope labeling is ideal for long-term studies and detailed analytical applications, including metabolic flux analysis and structural elucidation.

Choosing the Type of Synthesis Reagents

For more types of stable isotope labeling compounds, please check our isotopic product list directly.

Why Choose BOC Sciences' Isotope Labeled Synthesis Reagents?

Unmatched Expertise and Experience

BOC Sciences is a 20-year expert in the field of isotope labeling and synthesis. We are dedicated to offering high-tier, individual solutions created by our team of specialists in a scientific and compliant manner.

Cutting-Edge Technology

By using cutting-edge technology and advanced analytical methods, BOC Sciences guarantees the quality of isotope labeling services to our clients. We have state-of-the-art equipment for exact isotope incorporation and accurate measurement in our laboratories.

Comprehensive Services

We offer a wide array of service from custom labelling to state-of-art proteomics research. Our solutions are customized as per the need of every experiment to achieve maximum efficiency.

Commitment to Quality

We strive to continue offering products and services of the utmost quality. Our structured quality control processes and compliance with industry standards ensure that these isotope labeled synthesis reagents are reliable, reproducible in use.

FAQ

1. What is the isotope labeling method?

In order to gain information about chemical reactions or biological processes, one of the central techniques used is isotopic labelling - putting stable or radioactive isotopes into molecules that are then tracked through a reaction. The tracking of the isotopes through various stages provides insight into molecular interactions, reaction mechanisms and metabolic pathways.

2. What are isotope Labelled products?

Products that contain specific isotopes as part of their structure are isotope-labeled compounds. These labels are chemical or physical agents, most of the time stable isotopes ideally non-radioactive ones useful for research and diagnostics. They assist modelling molecular behaviour, metabolic networks and the chemical kinetics.

3. What is the effect of isotopic labeling?

Isotopic labeling of a molecule does not influence the chemical-reaction chemically reactive behavior but changes some physical properties like mass and nuclear spin. This enables the tracking, and analysis of labeled molecules in different systems with detailed information (metabolomics) at all levels for reactions to molecular mechanisms such as enzymatic or catalytic reaction kinetics and material transformations.

4. How are isotopically labeled compounds used to study metabolism?

Tracking the metabolism of these labeled molecules by isotopically labeling them to study how they are processed and transformed in biological systems For instance, a labeled glucose can be used to follow its transformation into other metabolites that would allow an evaluation of metabolic pathways or the activity and efficiency of different enzymes involved in those pathways.

5. How are isotopes labeled?

By replacing one of reporter no endogenous isotopes (C, H, O or N) present in the final metabolic compound with a stable/ radioactive isotope not naturally existing for this element. This is achieved through chemical synthesis (i.e., the desired isotope has to be built in into compound) or by methods specifically replacing certain atoms with isotopic analogs.

6. What are isotope Labelled chemicals?

Isotope-labeled chemicals are compounds in which one or more atoms have been replaced with isotopes. These labels, either stable or radioactive, enable researchers to track and analyze the chemical's behavior in various processes, such as metabolism or reaction pathways, by monitoring the isotopic signatures.

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