Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
BOC Sciences is committed to providing customers with isotope-labeled polymers. We offer a complete range of labeled polymers standards. All products come with comprehensive analytical data files and are of high chemical purity.
Isotope labeled polymers refer to replacing one or more atoms in polymer molecules with isotopes. Stable isotope labeled polymers are widely used, especially in the field of bio-medicine and plant research.
Polymers, also known as macromolecular compounds, mean those compounds with a relative molecular weight of more than 10000, which are mainly covalently bonded by many atoms or atomic groups. Polymers have three main characteristics. Firstly, in terms of relative molecular weight and composition, polymers have large relative molecular weights and polydispersities. Most polymers are polymerized from one or more monomers. Secondly, from the perspective of molecular structure, polymers include linear structure and body structure. Thirdly, in terms of properties, polymers have good mechanical strength because of their high relative molecular weight; polymers have good insulation and corrosion resistance because its molecules are covalently bonded; at the same time, because its molecular chain is very long and the ratio of molecular length to diameter is more than 1000, polymers have good plasticity and high elasticity.
Stable isotope labeled polymers are mainly used to improve the detection sensitivity and correct the change of mass spectrometry response. Because the physicochemical properties of stable isotope labeled polymers are completely consistent with the target polymers, their chromatography-mass spectrometry behavior is also consistent, which could effectively correct the fluctuation of detection response value possibly caused by complex matrix effect. Therefore, stable isotope labeled polymers are widely used in the fields of biological sample testing and tracing.
Isotope labeled polymers are mainly used to study the connection mode of chemical bonds in plants. For example, there are chemical bonds between lignin and carbohydrates in plant cell wall, and the complex formed makes it difficult to separate cellulose efficiently. Using stable isotopes to label lignin precursors and cellulose precursors, by means of isotopic detection of samples, the connection mode between lignin and cellulose could be explored, which is helpful to remove lignin more thoroughly.