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Steroides are category of organic compounds essential to many biological processes. Being able to examine these molecules in detail has provided tremendous advances in clinical diagnostics, pharmaceutical research and medical treatments. An additional potent tool for steroid research is the advent of labeled steroids. BOC Sciences is committed to providing customers with isotope-labeled steroids. We offer a complete range of labeled steroids standards, and the related products we provide include cholesterol, lanosterol, sitosterol, glucocorticoids, mineralocorticoids, sex hormones, etc. In addition, we also provide custom isotope labeling service for steroids, you can directly provide the steroid to be labeled or make a request such as the type of labeling isotope, the labeling site, and the isotope enrichment.
What is a Steroid?
Steroids are a general term for a large class of cyclopentane-fused perhydrophenanthrene derivatives widely distributed biologically. Steroids are commonly used in research for biology, medicine, pharmacy, and other fields due to their various physiological functions. Steroids are lipophilic organic compounds that include many hormones, alkaloids, and vitamins. They share a common structure composed of four fused carbon rings, known as a sterane or steroid nucleus.
Types of Steroids
- Cholesterol and Cholesterol Esters
Cholesterol is a crucial component of animal cells. Cholesterol is not only a precursor for synthesizing steroid compounds but is also involved in the formation of cell membranes. An appropriate amount of cholesterol is of great significance to maintaining the normal physiological functions of the human body. Cholesterol esters are esterification products of cholesterol and are the storage and transport form of cholesterol.
Sitosterol is a crucial component of plant cells and has the function of lowering cholesterol and preventing atherosclerosis.
Glucocorticoids mainly include cortisol and a small amount of corticosterone, which have a strong regulatory effect on blood sugar and various physiological functions, such as anti-inflammatory, anti-allergic, and anti-viral.
Mineralocorticoids have strong regulatory effects on water-salt balance, which mainly include aldosterone and deoxycorticosterone.
Sex hormones include androgens, estrogens, and progestins. Sex hormones play an important role in the growth and development of the body, as well as the growth and maturation of secondary sexual characteristics.
What are Isotope Labeled Steroids?
Isotope-labeled steroids are steroids that have been chemically modified to include stable isotopes, such as Deuterium (2H) or Carbon-13 (13C), within their molecular structure. These isotopes serve as tracers, allowing for the precise tracking and quantification of the steroids in various biological and chemical processes using techniques like mass spectrometry. The incorporation of stable isotopes does not alter the chemical properties of the steroids, making them ideal for use in detailed analytical studies. Isotope labeling techniques are widely used in the study of steroid metabolism. Using isotope-labeled steroids as internal standards, quantitative detection of steroids and metabolites can be achieved. This method upregulates the sensitivity and accuracy of quantitative detection of steroids and assists in disease monitoring, diagnosis, and treatment.
Our Isotope Labeling Services for Steroids
BOC Sciences excels in the production of stable labeled steroids, offering the largest selection of stable isotopes labeled products on the market. Our isotope labeling services include:
- Custom Synthesis: Tailored production of isotope-labeled steroids to meet specific research needs.
- Quality Assurance: Rigorous testing and validation to ensure the purity and accuracy of our labeled compounds.
- Comprehensive Support: Expert consultation to assist with the selection and application of isotope-labeled steroids in your research.
Choosing Labels for Your Research
Selecting the appropriate isotope label is crucial for the success of your experiments. Commonly used isotopes include:
In addition, the position of the isotope within the steroid molecule can affect the outcome of the analysis. Choose a labeling position that provides optimal sensitivity and specificity. Consider the analytical techniques you will use, such as mass spectrometry or nuclear magnetic resonance (NMR), and select isotopes that enhance the performance of these methods.
For more types of steroids and isotopic labeling, please contact us directly.
Applications of Isotope Labeled Steroids
Isotope-labeled steroids have a wide range of applications in scientific research and industry:
- Quantitative Analysis: Used in mass spectrometry for precise quantification of steroid concentrations in biological samples.
- Metabolic Studies: Track the metabolic pathways and degradation products of steroids within the body.
- Pharmaceutical R&D: Aid in the development of new drugs by studying the pharmacokinetics and pharmacodynamics of steroid compounds.
- Purity Profiling: Identify and quantify impurities in pharmaceutical formulations to ensure product safety and efficacy.
Why Choose BOC Sciences for the Synthesis of Your Isotope Labeled Steroids?
BOC Sciences stands out as a leading provider of isotope-labeled steroids due to our commitment to quality, innovation, and customer satisfaction. Here are some reasons to choose us:
- Extensive Selection: We offer the largest range of stable isotopes labeled steroids in the market.
- Expertise: Over 20 years of experience in the field, providing high-quality isotope-labeled compounds.
- Custom Solutions: Ability to tailor our products to meet the specific needs of your research.
- Compliance: Adherence to regulatory requirements for the production and shipment of controlled substances.
FAQ
1. What is isotope ratio mass spectrometry for steroids?
Isotope ratio mass spectrometry (IRMS) is a technique used to measure the relative abundance of isotopes in a sample. For steroids, IRMS can be used to determine the origin, metabolic pathways, and purity by analyzing the isotope ratios.
2. What are isotope Labelled standards?
Isotope-labeled standards are compounds that contain stable isotopes and are used as reference materials in analytical methods. They provide a benchmark for quantifying and identifying substances in complex mixtures.
3. What Does a Steroid Do?
Steroids perform a variety of functions in the body, including regulating metabolism, immune response, inflammation, and reproductive processes. They act by binding to specific receptors and influencing gene expression and protein synthesis.
4. What are the Three Types of Steroids?
The three main types of steroids are:
- Corticosteroids: Involved in the stress response and immune regulation.
- Sex Steroids: Include estrogens, androgens, and progestogens, which regulate reproductive functions.
- Anabolic Steroids: Promote muscle growth and physical performance.
5. What is the Safest Form of Steroids?
The safety of steroids depends on their intended use and administration. Topical corticosteroids, for example, are considered safe for treating skin conditions when used as directed.
