Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-007077 |
CAS: 2892630-35-0 |
Molecular Formula: C11[13C]H22O11 |
Molecular Weight: 343.29 |
Chemical Structure |
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Description | D-Cellobiose-[1'-13C] is intended for use as an internal standard for the quantification of D-Cellobiose, a diasccharide consisting of two glucose. |
Synonyms | D-Cellobiose-1'-13C; [1'-13C]cellobiose; D-[1'-13C]cellobiose |
IUPAC Name | (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy(6-13C)oxane-3,4,5-triol |
Related CAS | 528-50-7 (unlabelled) |
Canonical SMILES | C([C@@H]1[C@H]([C@@H]([C@H]([13C@@H](O1)O[C@@H]2[C@H](OC([C@@H]([C@H]2O)O)O)CO)O)O)O)O |
InChI | InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8-,9-,10-,11?,12+/m1/s1/i12+1 |
InChI Key | GUBGYTABKSRVRQ-QTUAQZHYSA-N |
Melting Point | 223-230 °C (dec.) |
D-Cellobiose-[1'-13C], a synthetic disaccharide with labeling, finds diverse applications in biochemical and industrial settings. Here are the key applications of D-Cellobiose-[1'-13C]:
Metabolic Pathway Tracing: Serving as a valuable tool for metabolic studies, D-Cellobiose-[1'-13C] aids in unraveling the intricacies of carbohydrate metabolism within organisms. Research endeavors involve tracking the 13C label across various biochemical reactions, shedding light on the complex pathways involved in the breakdown and synthesis of cellulose and other polysaccharides.
Nutrient Absorption Studies: Within the realm of nutritional science, D-Cellobiose-[1'-13C] plays a pivotal role in assessing carbohydrate absorption and digestion in the gastrointestinal tract. By administering the labeled compound and analyzing its absorption and subsequent metabolic products, researchers delve into digestive efficiency and nutrient uptake dynamics, offering insights into conditions like malabsorption syndromes and guiding dietary interventions.
Cellulose Degradation Research: Enzymology benefits from the use of D-Cellobiose-[1'-13C] as a tool to investigate cellulase activity, the enzymes responsible for breaking down cellulose. Through monitoring the degradation of the labeled disaccharide, scientists glean insights into enzyme kinetics and mechanisms essential for developing efficient strategies for biomass conversion and biofuel generation.
Structural Biology: In the realm of structural biology, D-Cellobiose-[1'-13C] serves as a valuable asset for NMR investigations into the structure and dynamics of polysaccharides and their interactions with proteins. The presence of the 13C label enhances the resolution and specificity of NMR signals, providing detailed insights into molecular conformation and binding sites. This knowledge catalyzes advancements in understanding carbohydrate-protein interactions and facilitates the design of innovative biocatalysts.
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