Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-010885 |
CAS: 90162-44-0 |
Molecular Formula: C8H6D4O |
Molecular Weight: 126.19 |
Chemical Structure |
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Description | 1-Phenylethanol-[d4] is the labelled analogue of 1-Phenylethanol. |
Synonyms | sec-Phenethyl-α,β,β,β-d4 alcohol; sec-Phenethyl-1,2,2,2-d4 alcohol |
IUPAC Name | 1,2,2,2-tetradeuterio-1-phenylethanol |
Related CAS | 98-85-1 (unlabelled) |
Canonical SMILES | CC(C1=CC=CC=C1)O |
InChI | InChI=1S/C8H10O/c1-7(9)8-5-3-2-4-6-8/h2-7,9H,1H3/i1D3,7D |
InChI Key | WAPNOHKVXSQRPX-CWIRFKENSA-N |
Boiling Point | 204°C at 745 mmHg |
Melting Point | 19-20°C |
Purity | 98% atom D |
Density | 1.045 g/cm3 at 25°C |
Storage | Store at RT |
1-Phenylethanol-[d4] is a deuterium-labeled analog of 1-phenylethanol, commonly used in research and analytical applications. Here are some key applications of 1-Phenylethanol-[d4]:
Stable Isotope Labeling: 1-Phenylethanol-[d4] is utilized in stable isotope labeling experiments for studying metabolic pathways and reaction mechanisms. It helps in tracing the incorporation and transformation of phenylethanol in biochemical processes. This approach provides insights into enzyme activity and metabolic flux.
NMR Spectroscopy: In NMR spectroscopy, 1-Phenylethanol-[d4] serves as an internal standard or reference compound due to its distinct shifts in the NMR spectra. This allows for precise quantification and structural elucidation of neighboring compounds in complex mixtures. The deuterium labeling enhances signal detection in spectroscopic analyses.
Pharmaceutical Research: Researchers use 1-Phenylethanol-[d4] in the study of drug metabolism and pharmacokinetics. It helps in elucidating the metabolic pathways and transformation products of drugs containing phenylethanol moieties. This information is crucial for understanding drug interactions and optimizing pharmacological profiles.
Synthetic Chemistry: In synthetic chemistry, 1-Phenylethanol-[d4] is applied as a labeled reagent for studying reaction mechanisms and kinetics. By incorporating deuterium, chemists can investigate reaction pathways and isotope effects. This aids in the design of more efficient synthetic routes and understanding catalytic processes.
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