Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-011306 |
CAS: 2260670-64-0 |
Molecular Formula: C37H71D4N10O17P3S |
Molecular Weight: 1061.07 |
Chemical Structure |
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Synonyms | palmitoyl(11,11,12,12-d4) Coenzyme A (ammonium salt); 9H-Purin-6-amine, 9-[(2ξ)-5-O-[hydroxy[[hydroxy[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-[[2-[(1-oxohexadecyl)thio]ethyl]amino]propyl]amino]butoxy]phosphinyl]oxy]phosphinyl]-3-O-phosphono-β-D-threo-pentofuranosyl]-, triammonium salt-11,11,12,12-d4; 16:0(d4) Coenzyme A |
IUPAC Name | triazanium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-[[[[(3R)-4-[[3-(2-hexadecanoylsulfanylethylamino)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-4-hydroxyoxolan-3-yl] hydrogen phosphate-11,11,12,12-d4 |
Related CAS | 799812-86-5 (unlabelled) |
Purity | >99% |
Solubility | Soluble in Chloroform, Methanol, Water |
Appearance | White Powder |
Shelf Life | 1 Year |
Storage | Store at -20°C |
16:0 Coenzyme A-[d4] Ammonium salt, a stable-isotope labeled compound, finds diverse applications in metabolic research and analytical chemistry. Here are key applications presented with high perplexity and burstiness:
Metabolic Flux Analysis: Utilizing 16:0 Coenzyme A-[d4] Ammonium salt as a tracer in metabolic flux analysis reveals insights into lipid metabolism at cellular and organismic levels. By incorporating this labeled compound, researchers unveil the intricate pathways of fatty acids, gaining a comprehensive understanding of their utilization and conversion within cellular environments. This detailed analysis not only highlights metabolic dysregulation but also unveils potential therapeutic targets for combating metabolic diseases like obesity and diabetes.
Lipidomics Studies: In the realm of lipidomics, the integration of 16:0 Coenzyme A-[d4] Ammonium salt facilitates the quantification and analysis of lipid species in complex biological matrices. By incorporating this compound into lipid molecules, researchers achieve precise measurements using mass spectrometry, shedding light on lipid composition and dynamics. This application plays a crucial role in decoding the functions of lipids in cellular processes and disease progression, propelling drug discovery and development forward with newfound insights.
Stable Isotope Labeling: Employing this compound in stable isotope labeling experiments unlocks the ability to explore protein-lipid interactions and lipid modifications with precision. By integrating stable isotopes, researchers can monitor shifts in lipid molecules during key biological processes like signaling and membrane dynamics. These in-depth studies are essential for unraveling the multifaceted roles of lipids in diverse cellular contexts and devising targeted interventions for lipid-related disorders, shaping the landscape of lipid research.
Biochemical Assays: Embedded within biochemical assays, 16:0 Coenzyme A-[d4] Ammonium salt plays a pivotal role in scrutinizing enzyme activities linked to fatty acid metabolism. Serving as a substrate in enzymatic reactions, this compound enables researchers to evaluate enzyme kinetics and metabolic regulations under varying conditions. This crucial information informs the design of tailored metabolic engineering strategies aimed at enhancing biotechnological applications such as biofuel production and industrial fermentation processes, driving innovation in the field of biochemical research.
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