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17:0-16:1 PC-[d5]

General Information
Catalog: BLP-011397
CAS: 2342575-79-3
Molecular Formula: C41H75D5NO8P
Molecular Weight: 751.09
Chemical Structure
17:0-16:1 PC-[d5]
Synonyms 1-heptadecanoyl-2-palmitoleoyl-sn-glycero(d5)-3-phosphocholine; 17:0-16:1 PC-d5; PC 17:0-16:1-d5; PC(17:0/16:1(9Z))-d5; 1-heptadecanoyl-2-(9Z-hexadecenoyl)-glycero-3-phosphocholine-d5
IUPAC Name [(2R)-1,1,2,3,3-pentadeuterio-3-heptadecanoyloxy-2-[(Z)-hexadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Canonical SMILES CCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCC
InChI InChI=1S/C41H80NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42(3,4)5)50-41(44)34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h17,19,39H,6-16,18,20-38H2,1-5H3/b19-17-/t39-/m1/s1/i37D2,38D2,39D
InChI Key DISVYZNGGMDUPX-FEZSZEOVSA-N
Purity >99%
Solubility Soluble in DCM, Methanol
Appearance Liquid
Shelf Life 1 Year
Storage Store at -20°C

17:0-16:1 PC-[d5], a deuterated phosphatidylcholine lipid, stands at the forefront of scientific and industrial research realms. Here are key applications of 17:0-16:1 PC-[d5] presented with high perplexity and burstiness:

Lipidomics Research: Embarking on the complex voyage of lipidomics, 17:0-16:1 PC-[d5] emerges as a pivotal internal standard, enabling the meticulous quantification of lipids in biological samples. Its unique mass, a consequence of deuteration, facilitates precise measurement in mass spectrometry-based analyses. This precision empowers researchers to delve deep into lipid metabolism profiles, illuminating the intricate role of lipids in both realms of health and disease scenarios.

Membrane Dynamics Studies: In the realm of cellular membrane dynamics, 17:0-16:1 PC-[d5] emerges as a steadfast ally, offering profound insights into the distribution and dynamics of lipids within cellular membranes. By integrating this specially labeled lipid into model membranes, scientists embark on a captivating journey to unravel the intricacies of membrane organization, fluidity dynamics, and interactions with proteins—laying the groundwork to comprehend the intricate mechanisms underlying vital membrane-related processes such as cell signaling cascades.

Pharmacokinetics: Positioned on the cutting edge of drug development, 17:0-16:1 PC-[d5] emerges as an indispensable tool for dissecting the pharmacokinetics and biodistribution patterns of lipid-based drug delivery systems. By employing this deuterated lipid as a guiding beacon, researchers deftly navigate the complexities of how drugs loaded within lipid carriers traverse distribution pathways and metabolic processes within the human body. This invaluable insight propels the optimization of drug formulation strategies and delivery mechanisms, heralding a new era of precision medicine.

Environmental Toxicology: The domain of environmental toxicology witnesses the enlightening influence of 17:0-16:1 PC-[d5], facilitating the assessment of bioaccumulation and unveiling the disruptive effects of contaminants on lipid profiles within organisms. By tracing the fingerprints left by environmental toxins on lipid metabolism, researchers deepen their comprehension of the intricate interplay between toxins and cellular functions, paving the way toward crafting robust strategies to mitigate the ecological impacts of pollutants on our delicate ecosystem.

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