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2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline-[d3]

General Information
Catalog: BLP-007811
CAS: 1216997-87-3
Molecular Formula: C12H10D3N5
Molecular Weight: 230.28
Chemical Structure
2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline-[d3]
Description 2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline is a mutagenic/carcinogenic heterocyclic amine formation found in fried beef steak.
Synonyms 3-(D3)methyl-4,8-dimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine
IUPAC Name 4,8-dimethyl-3-(trideuteriomethyl)imidazo[4,5-f]quinoxalin-2-amine
Related CAS 95896-78-9 (unlabelled)
Canonical SMILES CC1=CC2=NC=C(N=C2C3=C1N(C(=N3)N)C)C
InChI InChI=1S/C12H13N5/c1-6-4-8-9(15-7(2)5-14-8)10-11(6)17(3)12(13)16-10/h4-5H,1-3H3,(H2,13,16)/i3D3
InChI Key LAZSIJHHPMHKQI-HPRDVNIFSA-N
Melting Point >260°C
Purity >98%
Solubility Soluble in DMSO, Methanol
Appearance Green Solid
Storage Store at -20°C

2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline-[d3] is a specialized compound utilized in various scientific applications. Here are some key applications of this compound:

Cancer Research: This compound is used in cancer research to investigate its effects on cellular processes related to carcinogenesis. By studying its interactions with DNA and cellular pathways, researchers can assess its potential as a chemotherapeutic agent. It may help in understanding molecular mechanisms involved in tumor progression and drug resistance.

Pharmacokinetic Studies: In drug development, this compound serves as a tracer in pharmacokinetic studies due to its stable isotopic labeling with deuterium. Researchers use it to track the absorption, distribution, metabolism, and excretion of pharmaceuticals. This information is essential for optimizing dosage regimens and ensuring drug safety and efficacy.

Chemical Synthesis: 2-Amino-3,4,8-trimethyl-3H-imidazo[4,5-f]quinoxaline-[d3] can be used as an intermediate in the synthesis of more complex compounds. Its unique structure allows chemists to explore new synthetic pathways leading to the discovery of novel molecules. This application is particularly valuable in the development of new drugs and materials.

Environmental Testing: In environmental science, this compound can be employed to study the degradation and persistence of quinoxaline derivatives in ecosystems. By using isotopically labeled versions, scientists can accurately trace and model their behavior in soil and water. These insights are crucial for assessing environmental impact and establishing regulations for chemical contaminants.

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