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2-Bromo-1,3-bis(tert-butyldimethylsilyloxy)propane-[d4]

General Information
Catalog: BLP-006399
CAS: 1794816-65-1
Molecular Formula: C15H31D4BrO2Si2
Molecular Weight: 387.54
Chemical Structure
2-Bromo-1,3-bis(tert-butyldimethylsilyloxy)propane-[d4]
Synonyms 2-Bromo-1,3-bis(tert-butyldimethylsilyloxy)propane-d4
IUPAC Name [2-bromo-3-[tert-butyl(dimethyl)silyl]oxy-1,1,3,3-tetradeuteriopropoxy]-tert-butyl-dimethylsilane
Related CAS 1433849-96-7 (unlabelled)
Canonical SMILES CC(C)(C)[Si](C)(C)OCC(CO[Si](C)(C)C(C)(C)C)Br
InChI InChI=1S/C15H35BrO2Si2/c1-14(2,3)19(7,8)17-11-13(16)12-18-20(9,10)15(4,5)6/h13H,11-12H2,1-10H3/i11D2,12D2
InChI Key SUXFIDUKDVMDFI-AREBVXNXSA-N
Purity 98%
Solubility Soluble in Chloroform, Dichloromethane, Methanol
Appearance Yellow Oily Matter
Storage Store at -20°C

2-Bromo-1,3-bis(tert-butyldimethylsilyloxy)propane-[d4], a deuterated chemical compound utilized predominantly in chemical research and synthesis. Here are key applications of 2-Bromo-1,3-bis(tert-butyldimethylsilyloxy)propane-[d4] presented with high perplexity and burstiness:

Isotopic Labeling: This compound serves as a cornerstone in isotopic labeling endeavors, where researchers harness deuterated molecules to interrogate intricate reaction mechanisms. The introduction of deuterium atoms facilitates meticulous scrutiny in spectroscopy, offering profound insights into molecular interactions and metamorphoses. This application stands as a linchpin for unpicking the dynamic intricacies within organic chemistry.

Organic Synthesis: Embodying the role of a safeguarded bromohydrin derivative, this compound finds its niche in the synthesis of convoluted organic compounds. The tert-butyldimethylsilyloxy groups play the vital role of sentinels during reactions, enabling discerning functional group metamorphoses. Particularly invaluable in multistep synthesis pathways, where preserving the sanctity of reactive groups reigns paramount.

NMR Spectroscopy: Deuterated compounds, this being no exception, wield high value in nuclear magnetic resonance (NMR) spectroscopy for scrutinizing molecular architectures. The presence of deuterium acts as a mute button for background signals, refining the lucidity and veracity of spectral data. Its aid in precise chemical shift characterizations and structural unraveling is indispensable.

Pharmaceutical Research: Integral to drug development, this compound is harnessed for synthesizing labeled intermediates and prodding metabolic roadways. Leveraging deuterated compounds can unlock insights into the stability and dispersal of pharmaceutical contenders. This intelligence lays the foundation for fine-tuning drug blueprints and unraveling the enigma of pharmacokinetics.

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