2-Keto-3-(methyl-[d3])-butyric acid-4-[13C],3-[d] sodium salt

2-Keto-3-(methyl-[d3])-butyric acid-4-[13C],3-[d] sodium salt, a labeled chemical compound widely utilized in metabolic research and isotope labeling studies, boasts a plethora of applications. Here we explore key applications presented with high perplexity and burstiness:

Stable Isotope Tracing: In the intricate realm of metabolic flux analysis, this compound plays a pivotal role in elucidating pathways and unraveling the intricacies of metabolic networks. By integrating stable isotopes, researchers embark on a journey to monitor the distribution and transformation of metabolites within biological systems. This technique is indispensable, shedding light on metabolic bottlenecks and optimizing pathways for enhanced bioproduction.

Pharmaceutical Research: At the forefront of drug metabolism studies, the labeled 2-keto acid emerges as an indispensable tool for investigating the pharmacokinetics of pharmaceuticals. It enables scientists to meticulously track the metabolic destiny of drug compounds, both in vitro and in vivo. By deciphering drug metabolism pathways, researchers lay the groundwork for enhancing drug design efficacy and safety, driving innovation in pharmacology.

Biochemical Studies: Delving into the realm of enzymatic assays, this compound serves as a cornerstone for studying the activity and kinetics of enzymes involved in keto acid metabolism. It offers profound insights into enzyme mechanisms and their pivotal roles in metabolic processes. Such studies hold immense value in the development of enzyme modulators that could potentially serve as therapeutic interventions, showcasing the intricate dance of biochemistry.

Nutrition and Health Research: Embracing the labeled sodium salt variant of this compound, researchers delve into human and animal nutritional studies to evaluate amino acid and protein metabolism. By analyzing the metabolic integration and excretion of labeled substrates, researchers glean insights into nutritional demands and metabolic anomalies. This application drives strides in personalized nutrition and tailored dietary recommendations, nurturing advancements in health and wellness research.