Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-010403 |
CAS: 7329-52-4 |
Molecular Formula: C7H4D4O2 |
Molecular Weight: 128.16 |
Chemical Structure |
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Description | 2-Methoxyphenol-[3,4,5,6-d4] is the labelled analogue of Guaiacol. Guaiacol is an agent that is believed to have disinfecting properties and is used as an expectorant. |
Synonyms | 2-Methoxyphenol-3,4,5,6-D4; d4-2-methoxyphenol; Phen-2,3,4,5-d4-ol, 6-methoxy-; 2-Hydroxyanisole-d4; Anastil-d4; Guaiacol-d4; Guaiastil-d4; Methylcatechol-d4; o-Hydroxyanisole-d4; O-Methoxyphenol-d4; NSC 3815-d4; o-Methoxy-phenol-d4 |
IUPAC Name | 2,3,4,5-tetradeuterio-6-methoxyphenol |
Related CAS | 90-05-1 (unlabelled) |
Canonical SMILES | COC1=CC=CC=C1O |
InChI | InChI=1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3/i2D,3D,4D,5D |
InChI Key | LHGVFZTZFXWLCP-QFFDRWTDSA-N |
Purity | ≥95%; 98% atom D |
Solubility | Slightly soluble in Chloroform, Methanol |
Appearance | Orange Oily Matter |
Storage | Store at 2-8°C under inert atmosphere |
2-Methoxyphenol-[3,4,5,6-d4] is a deuterated compound that finds use in various scientific applications, especially in analytical chemistry and research. Here are some key applications of 2-Methoxyphenol-[3,4,5,6-d4]:
Stable Isotope Labeling: In research involving stable isotope labeling, 2-Methoxyphenol-[3,4,5,6-d4] acts as a critical standard. Its deuterium atoms serve as tracers in mass spectrometry to facilitate the quantification of phenol compounds in complex mixtures. This allows for accurate studies of metabolic pathways and chemical transformations.
NMR Spectroscopy: 2-Methoxyphenol-[3,4,5,6-d4] is utilized in nuclear magnetic resonance (NMR) spectroscopy as a reference compound. The deuterium labeling helps in reducing signal interference, providing clearer results and enhancing spectral analysis. Researchers use this information to investigate molecular structures and dynamics more effectively.
Pharmacokinetic Studies: The deuterated nature of 2-Methoxyphenol-[3,4,5,6-d4] makes it valuable in pharmacokinetic research. It serves as a non-radioactive marker in the study of drug absorption, distribution, metabolism, and excretion. This application aids in better understanding the biodistribution and metabolic fate of drugs.
Environmental Analysis: In environmental chemistry, 2-Methoxyphenol-[3,4,5,6-d4] can be employed to track phenolic pollutants. It serves as an internal standard in gas or liquid chromatography to accurately quantify phenolic contaminants in air, water, and soil samples. This contributes to monitoring and managing environmental pollution effectively.
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