3-Chloro-L-tyrosine-[13C6]

3-Chloro-L-tyrosine-[13C6] is a labeled amino acid used in various scientific research and analytical applications. Here are some key applications of 3-Chloro-L-tyrosine-[13C6]:

Stable Isotope Labeling: 3-Chloro-L-tyrosine-[13C6] is employed as a stable isotope-labeled amino acid in proteomics and metabolic research. By incorporating this compound into proteins, researchers can trace metabolic pathways and quantitatively analyze protein dynamics using mass spectrometry. This technique is invaluable for understanding protein turnover and metabolic fluxes in complex biological systems.

Analytical Chemistry: In analytical chemistry, 3-Chloro-L-tyrosine-[13C6] serves as an internal standard for quantitative analyses of amino acids and related compounds. Its incorporation helps in correcting for matrix effects and ensuring precision in measurements. This enhances the accuracy and reliability of analytical methods used in environmental, food, and clinical sample assessments.

Pharmaceutical Research: 3-Chloro-L-tyrosine-[13C6] is used in pharmaceutical research to study drug metabolism and pharmacokinetics. By incorporating the labeled compound into drugs, researchers can track and analyze the distribution, absorption, and breakdown of pharmaceuticals within the body. This information is crucial for drug development and optimizing therapeutic regimens.

Biochemical Pathway Analysis: Researchers use 3-Chloro-L-tyrosine-[13C6] to investigate the biochemical pathways involving chlorinated tyrosine derivatives. Its presence allows scientists to study enzyme kinetics and substrate specificities in reactions involving halogenated amino acids. This contributes to a deeper understanding of biochemical transformations and the influence of halogenation on enzyme activity.