3-Nitro-L-tyrosine-[ring-13C6]

3-Nitro-L-tyrosine-[ring-13C6], a stable isotope-labeled compound, finds diverse applications in scientific and research domains. Explore its key applications through a lens of high perplexity and burstiness:

Proteomics and Mass Spectrometry: Positioned as an internal standard in proteomics, 3-Nitro-L-tyrosine-[ring-13C6] stands as a pivotal tool for quantifying protein nitration – a crucial post-translational modification entwined with oxidative stress investigations. By leveraging this labeled compound, researchers navigate the intricate realm of distinguishing nitration from kin modifications, unlocking precise quantification and deep analysis of protein samples nestled within complex biological concoctions.

Biomarker Discovery: Within the realm of clinical research, 3-Nitro-L-tyrosine-[ring-13C6] emerges as a beacon for unraveling nitration patterns present in maladies like cardiovascular disorders and neurodegenerative conditions. It serves as a cornerstone for validating prospective biomarkers entwined with oxidative stress-related ailments, ushering in an era of heightened accuracy in disease mechanism comprehension and progression understanding.

Environmental Analysis: A stalwart ally in environmental explorations, 3-Nitro-L-tyrosine-[ring-13C6] takes center stage in tracing and quantifying nitrated tyrosine residues within a plethora of samples spanning water bodies to soil landscapes. The stable isotope labeling wielded by this compound unveils a world where nitrated compounds within complex environmental fabrics are laid bare. This aids in evaluating environmental exposure to nitrating agents, shedding light on their potential ecological ripples in the grand scheme of environmental integrity.

Pharmaceutical Research: Stepping into the domain of pharmaceutical innovation, this compound plays a transformative role in crafting and scrutinizing drugs aimed at combating nitration-induced pathways within oxidative stress milieus. Through the lens of 3-Nitro-L-tyrosine-[ring-13C6], researchers embark on a journey to unravel the pharmacokinetic nuances and efficacy realms of potential therapeutic agents. This contribution stands as a cornerstone for pioneering novel treatments tailored to address diseases marred by the adversities of oxidative stress, heralding a new dawn in the domain of healthcare advancements.