Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-011869 |
CAS: 1219804-13-3 |
Molecular Formula: C7D6ClF |
Molecular Weight: 150.61 |
Chemical Structure |
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Description | Fluorobenzyl-[d6] chloride is the labelled analogue of 4-Fluorobenzyl Chloride, which is a chemical intermediate in the synthesis of various pharmaceutical and agricultural goods. |
Synonyms | Fluorobenzyl-D6 chloride |
IUPAC Name | 1-[chloro(dideuterio)methyl]-2,3,5,6-tetradeuterio-4-fluorobenzene |
Related CAS | 352-11-4 (unlabelled) |
Canonical SMILES | C1=CC(=CC=C1CCl)F |
InChI | InChI=1S/C7H6ClF/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2/i1D,2D,3D,4D,5D2 |
InChI Key | IZXWCDITFDNEBY-NVSFMWKBSA-N |
Boiling Point | 181.6±15.0 °C at 760 mmHg |
Purity | 95% |
Density | 1.2±0.1 g/cm3 |
Storage | Store at -20°C |
Fluorobenzyl-[d6] chloride is a deuterated chemical compound that finds significant applications in various scientific fields. Here are some key applications of Fluorobenzyl-[d6] chloride:
Analytical Chemistry: Fluorobenzyl-[d6] chloride is widely used in analytical chemistry as a labeling reagent. By incorporating deuterium atoms, it serves as an isotopic label in mass spectrometry, aiding in the identification and quantification of compounds. This application is crucial for studying complex mixtures and tracing metabolic pathways.
Pharmaceutical Research: In drug development, Fluorobenzyl-[d6] chloride is utilized to synthesize deuterium-labeled pharmaceuticals. These labeled compounds are important for pharmacokinetic and metabolic studies, providing insights into drug absorption, distribution, metabolism, and excretion. Deuterium-labeled drugs can reveal subtle differences in biological processes compared to their non-labeled counterparts.
Nuclear Magnetic Resonance (NMR) Spectroscopy: The use of Fluorobenzyl-[d6] chloride in NMR spectroscopy enhances the quality of spectral data. Deuterium labeling reduces line broadening and simplifies spectra, facilitating the study of molecular structures and dynamics. This application is especially useful in complex samples where detailed structural information is required.
Radiopharmaceutical Research: Fluorobenzyl-[d6] chloride plays an important role in the development of radiolabeled compounds for imaging studies. By substituting hydrogen with deuterium, researchers can design stable isotopes that are suitable for positron emission tomography (PET) and other imaging techniques. These radiopharmaceuticals are vital for non-invasive diagnosis and monitoring of diseases.
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