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4-Hydroxybenzaldehyde-[d6]

General Information
Catalog: BLP-005759
CAS: 284474-48-2
Molecular Formula: C7D6O2
Molecular Weight: 128.16
Chemical Structure
4-Hydroxybenzaldehyde-[d6]
Description 4-Hydroxybenzaldehyde-[d6] is an isotope analogue of 4-Hydroxybenzaldehyde (p-Hydroxybenzaldehyde). p-Hydroxybenzaldehyde is one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
IUPAC Name deuterio-(2,3,5,6-tetradeuterio-4-deuteriooxyphenyl)methanone
Related CAS 123-08-0 (unlabelled)
Isomeric SMILES [2H]C1=C(C(=C(C(=C1C(=O)[2H])[2H])[2H])O[2H])[2H]
Canonical SMILES C1=CC(=CC=C1C=O)O
InChI InChI=1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H/i1D,2D,3D,4D,5D/hD
InChI Key RGHHSNMVTDWUBI-QNKSCLMFSA-N
Melting Point 117-119°C
Purity 99% by CP; 99% atom D
Appearance White Solid

4-Hydroxybenzaldehyde-[d6], a deuterated variant of 4-hydroxybenzaldehyde, is extensively utilized in research and industrial settings. Here we delve into key applications of 4-Hydroxybenzaldehyde-[d6] with heightened perplexity and burstiness:

Stable Isotope Labeling: At the forefront of stable isotope labeling experiments vital for metabolomics and proteomics research, 4-Hydroxybenzaldehyde-[d6] plays an indispensable role. By aiding in the tracking of metabolic pathways and protein interactions with exceptional precision, this compound enables researchers to delve into complex biological systems and uncover potential disease biomarkers in meticulous detail. The incorporation of deuterium into molecules allows for exploration using cutting-edge mass spectrometry techniques, pushing the boundaries of scientific discovery.

NMR Spectroscopy: Within the intricate domain of NMR spectroscopy, 4-Hydroxybenzaldehyde-[d6] shines as an essential internal standard thanks to its deuterated composition. The unique spectral properties bestowed by deuterium make this compound a perfect reference for accurate interpretation of intricate spectra, providing insights into the structure and dynamics of organic compounds through advanced spectroscopic analyses. This compound opens doors to a deeper understanding of molecular intricacies through detailed spectroscopic examinations.

Organic Synthesis: In the realm of organic chemistry, 4-Hydroxybenzaldehyde-[d6] serves as a fundamental building block for synthesizing sophisticated deuterated compounds. Acting as a precursor in chemical reactions, it facilitates the introduction of the deuterated benzaldehyde moiety into larger molecules, a critical process for pharmaceutical synthesis and labeling. This application holds particular significance in drug metabolism studies and tracking of pharmaceuticals for research purposes, offering a nuanced perspective on compound interactions and transformations.

Pharmacokinetic Studies: Within the realm of pharmacokinetic research, 4-Hydroxybenzaldehyde-[d6] plays a pivotal role in investigating drug absorption, distribution, metabolism, and excretion (ADME). Deuterated compounds like this one provide a crucial distinction between the drug and its metabolites during analysis, offering essential insights for optimizing drug delivery methods and dosage regimens. This ultimately leads to the development of safer and more efficacious therapeutics, revolutionizing the landscape of pharmaceutical research and development with a focus on precision and efficacy.

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