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5-Methylchrysene-[methyl-d3]

General Information
Catalog: BLP-007139
Molecular Formula: C19H11D3
Molecular Weight: 245.33
Chemical Structure
5-Methylchrysene-[methyl-d3]
Description 5-Methylchrysene-[methyl-d3] is the labelled salt of 5-Methylchrysene, which is a carcinogenic polycyclic aromatic hydrocarbon consisting of four fused rings and acts as an aryl hydrocarbon receptor agonist.
Synonyms 5-Methylchrysene (methyl-D3)
IUPAC Name 5-(methyl-d3)chrysene
Related CAS 3697-24-3 (unlabelled)
Melting Point 116-118°C
Purity 98% by CP; 98% atom D
Solubility Soluble in Chloroform, Methanol
Appearance White to Off-white Solid
Storage Store at -20°C

5-Methylchrysene-[methyl-d3], a deuterium-labeled polycyclic aromatic hydrocarbon (PAH) utilized in scientific research, particularly in the exploration of environmental carcinogens and metabolism. Here are key applications of 5-Methylchrysene-[methyl-d3] presented with high perplexity and burstiness:

Metabolism Studies: Delving into the intricacies of PAH metabolism, 5-Methylchrysene-[methyl-d3] is a cornerstone in deciphering how these compounds undergo processing within biological systems. By tracing the incorporation of deuterium, researchers unveil metabolic pathways and unravel the identities of metabolites. This knowledge is pivotal in evaluating the biological repercussions and carcinogenic potentials of PAHs.

Carcinogenicity Research: At the forefront of oncological exploration, this labeled compound is integral to studies aimed at unraveling the enigmatic mechanisms behind PAH-induced carcinogenesis. Researchers harness 5-Methylchrysene-[methyl-d3] to probe into DNA binding and adduct formation, pivotal stages in cancer progression. These investigations inform risk evaluations and shape the development of intervention strategies against PAH-related malignancies.

Analytical Chemistry: Within the realm of analytical laboratories, 5-Methylchrysene-[methyl-d3] assumes a crucial role as an internal standard or tracer. Its incorporation in methodologies like mass spectrometry enables precise quantification and detection of PAHs within intricate environmental samples. This application stands as a vital component in monitoring PAH contamination and accurately evaluating environmental exposure risks.

Environmental Fate and Transport: Research endeavors rely on 5-Methylchrysene-[methyl-d3] to unravel the behaviors and transportation patterns of PAHs in environmental settings. By infusing PAHs with stable isotopes, scientists can meticulously track the movements of these compounds through soil, water, and air systems. This painstaking research aids in comprehending the persistence and dispersion of PAHs, crucial in environmental risk assessments and the formulation of effective remediation strategies.

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