7-Dehydrocholesterol-[d6]

7-Dehydrocholesterol-[d6], a deuterated derivative of 7-dehydrocholesterol, serves as a key isotopic standard and tracer in diverse biochemical applications:

Cholesterol Metabolism Research: Delve into the intricate world of cholesterol biosynthesis and metabolic pathways using 7-Dehydrocholesterol-[d6]. By incorporating this labeled compound, researchers can meticulously trace the conversion processes and quantify the intermediates involved in cholesterol metabolism. Gain profound insights into the dynamic equilibrium of cholesterol homeostasis and unravel the intricate web of genetic or pharmacological interventions impacting these pathways.

Vitamin D Studies: Embark on a journey through the realm of vitamin D biosynthesis with 7-Dehydrocholesterol-[d6], a vital precursor to this essential vitamin. Researchers harness the power of this deuterated compound to unravel the mysteries of vitamin D3 synthesis in the skin. Dive deep into the photochemical conversion processes triggered by UV exposure and measure the synthesis rates to decipher the multifaceted factors influencing vitamin D production and the efficacy of supplementation strategies.

Isotope Dilution Mass Spectrometry: Step into the world of precise quantification with 7-Dehydrocholesterol-[d6] as your isotopic internal standard in mass spectrometry assays. By utilizing this deuterated standard, scientists can achieve unparalleled accuracy in quantifying cholesterol and its derivatives in biological samples. Elevate the reliability and reproducibility of analytical measurements, critical pillars supporting clinical diagnostics and metabolic research.

Pharmaceutical Development: Unveil the secrets of drug metabolism and pharmacokinetics using the labeled compound 7-Dehydrocholesterol-[d6]. Researchers wield this invaluable tool to unravel the absorption, distribution, metabolism, and excretion (ADME) of cholesterol-related pharmaceuticals. This knowledge forms the bedrock for optimizing drug formulations and unraveling their intricate dance within the human body, paving the way for enhanced drug efficacy and safety.