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Ammonium-[d4] bromide

General Information
Catalog: BLP-009179
CAS: 12265-06-4
Molecular Formula: ND4Br
Molecular Weight: 101.97
Chemical Structure
Ammonium-[d4] bromide
Synonyms AMMONIUM-D4 BROMIDE; AMMONIUM BROMIDE-D4; Ammoniumbromide((ND4)Br); AMMONIUM-D4 BROMIDE, 98+ ATOM % D; Ammonium-D4 bromide >99.0 Atom % D; AMMONIUM-D4 BROMIDE, 98+ ATOM% D, FOR NMR
IUPAC Name tetradeuterioazanium;bromide
Related CAS 12124-97-9 (unlabelled)
Isomeric SMILES [2H][N+]([2H])([2H])[2H].[Br-]
Canonical SMILES [NH4+].[Br-]
InChI InChI=1S/BrH.H3N/h1H;1H3/i/hD4
InChI Key SWLVFNYSXGMGBS-JBISRTOLSA-N
Melting Point 452°C (subl.) (lit.)
Purity 98% atom D
Density 2.528 g/cm3
Appearance white powder

Ammonium-[d4] bromide, a deuterated compound utilized primarily in scientific research and analytical applications, presents various key applications. Here are key applications presented with high perplexity and burstiness:

Stable Isotope Labeling: Ammonium-[d4] bromide finds its niche in stable isotope labeling studies, especially in the realm of mass spectrometry. By integrating deuterium, researchers can meticulously trace and quantify metabolic pathways, unraveling the destinies of nitrogen-containing compounds in biological systems. This intricate process sheds light on the convoluted biochemical mechanisms, facilitating comprehensive metabolic profiling.

NMR Spectroscopy: Within the domain of nuclear magnetic resonance (NMR) spectroscopy, deuterated compounds like Ammonium-[d4] bromide take center stage in minimizing background signals. The inclusion of deuterium enables clearer spectroscopic analyses, reducing interference from hydrogen protons and enhancing the accuracy and resolution of NMR experiments. This optimization streamlines the study of molecular structures and interactions, offering deeper insights into the intricacies of chemical compositions.

Pharmaceutical Research: Ammonium-[d4] bromide plays a pivotal role in both the synthesis and analysis of deuterated pharmaceuticals. Deuterium integration can significantly impact the pharmacokinetics and metabolism of drugs, ultimately enhancing their efficacy and lowering toxicity levels. This application stands as a cornerstone in the creation of novel therapeutic agents endowed with enhanced properties, pushing the boundaries of pharmaceutical research and development.

Environmental Chemistry: In the sphere of environmental studies, Ammonium-[d4] bromide serves as a vital tracer for monitoring the behaviors and distributions of ammonium compounds in ecosystems. Through deuterium labeling, scientists can delve into nitrogen cycling, pinpoint pollution sources, and gauge the repercussions of agricultural practices on environmental sustainability. This robust approach aids in unraveling ecological processes, contributing to the assessment of environmental well-being and fostering sustainable practices.

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