D-glucitol-[1,1'-d2]

D-glucitol-[1,1'-d2], also recognized as deuterated sorbitol, stands as a stable isotope-labeled compound holding diverse applications across scientific research and industry. Here are the key applications of D-glucitol-[1,1'-d2]:

Metabolic Tracing: Acting as a metabolic tracer within biochemical investigations, D-glucitol-[1,1'-d2] allows for the precise monitoring of carbohydrate flux within metabolic pathways. By integrating this deuterium-laden compound into metabolic experiments, researchers unveil its metamorphosis into a myriad of metabolites. This insightful process sheds light on carbohydrate metabolism intricacies, offering pivotal aid in unraveling the mysteries of metabolic disorders.

NMR Spectroscopy: Within the realm of nuclear magnetic resonance (NMR) spectroscopy, D-glucitol-[1,1'-d2] assumes a crucial role in enhancing the structural elucidation of intricate molecules. The deuterium atoms substitution for hydrogen effectively diminishes background signals, thereby elevating spectral resolution. This enhancement facilitates detailed structural scrutiny and compound characterization, proving indispensable in both research and industrial environments.

Pharmacokinetics: Delving into pharmacokinetic studies, D-glucitol-[1,1'-d2] serves as a pivotal tool in comprehending the absorption, distribution, metabolism, and excretion of sugar alcohols within the human body. Through the administration of this labeled compound, researchers meticulously trail its journey and transformations within biological systems. Such nuanced information forms the foundation for crafting novel formulations and dosage strategies for sugar alcohol-based pharmaceuticals and food adjuncts.

Analytical Chemistry: At the heart of analytical chemistry, D-glucitol-[1,1'-d2] emerges as an internal standard in mass spectrometry and various analytical methodologies. Thanks to its stable isotope label, accurate quantification and comparison of analytes within complex mixtures become achievable. This application plays a pivotal role in quality assurance, guaranteeing the precision and trustworthiness of analytical measurements across diverse industries such as pharmaceuticals and food science.