Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013281 |
Molecular Formula: C5[13C]H14O6 |
Molecular Weight: 183.17 |
Chemical Structure |
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Description | A labelled analogue of D-allitol. Allitol is isolated from the herb of Itea yunnanensis Franch. It is an important intermediate of some medicines against diabetes, cancer, and viral infections, including AIDS. |
Synonyms | D-[1-13C]allitol; L-[6-13C]allitol; D-allitol-1-13C |
Related CAS | 488-44-8 (unlabelled) |
D-allitol-[1-13C] is a carbon-13 labeled sugar alcohol used primarily in research settings to track metabolic pathways and study enzyme activity. Here are some key applications of D-allitol-[1-13C]:
Metabolic Flux Analysis: D-allitol-[1-13C] is instrumental in tracing metabolic pathways within organisms. By monitoring the labeled carbon atom, researchers can analyze the distribution and conversion of metabolites through different biochemical routes. This method helps in understanding cellular metabolism and identifying metabolic bottlenecks.
Enzyme Kinetics Studies: In enzymology, D-allitol-[1-13C] is used to study the kinetics and specificity of enzymes that interact with sugar alcohols. By observing how the labeled compound is processed by enzymes, scientists can gain insights into reaction mechanisms and substrate preferences. This information is crucial for designing inhibitors or enhancers for therapeutic purposes.
Isotopic Labeling Experiments: D-allitol-[1-13C] is valuable for isotopic labeling experiments aimed at elucidating complex biochemical networks. When incorporated into metabolic pathways, the labeled carbon can be detected using advanced spectroscopic techniques such as NMR or mass spectrometry. These experiments provide detailed information on metabolic fluxes and enzyme activities.
Nutritional Research: D-allitol-[1-13C] can be utilized in nutritional studies to investigate the metabolism and health effects of sugar alcohols. By following the labeled carbon through metabolic processes, scientists can better understand the digestion, absorption, and utilization of sugar alcohols in the body. This research is important for developing dietary recommendations and therapeutic interventions for metabolic disorders.
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