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D-allitol-[1-13C]

General Information
Catalog: BLP-013281
Molecular Formula: C5[13C]H14O6
Molecular Weight: 183.17
Chemical Structure
D-allitol-[1-13C]
Description A labelled analogue of D-allitol. Allitol is isolated from the herb of Itea yunnanensis Franch. It is an important intermediate of some medicines against diabetes, cancer, and viral infections, including AIDS.
Synonyms D-[1-13C]allitol; L-[6-13C]allitol; D-allitol-1-13C
Related CAS 488-44-8 (unlabelled)

D-allitol-[1-13C] is a carbon-13 labeled sugar alcohol used primarily in research settings to track metabolic pathways and study enzyme activity. Here are some key applications of D-allitol-[1-13C]:

Metabolic Flux Analysis: D-allitol-[1-13C] is instrumental in tracing metabolic pathways within organisms. By monitoring the labeled carbon atom, researchers can analyze the distribution and conversion of metabolites through different biochemical routes. This method helps in understanding cellular metabolism and identifying metabolic bottlenecks.

Enzyme Kinetics Studies: In enzymology, D-allitol-[1-13C] is used to study the kinetics and specificity of enzymes that interact with sugar alcohols. By observing how the labeled compound is processed by enzymes, scientists can gain insights into reaction mechanisms and substrate preferences. This information is crucial for designing inhibitors or enhancers for therapeutic purposes.

Isotopic Labeling Experiments: D-allitol-[1-13C] is valuable for isotopic labeling experiments aimed at elucidating complex biochemical networks. When incorporated into metabolic pathways, the labeled carbon can be detected using advanced spectroscopic techniques such as NMR or mass spectrometry. These experiments provide detailed information on metabolic fluxes and enzyme activities.

Nutritional Research: D-allitol-[1-13C] can be utilized in nutritional studies to investigate the metabolism and health effects of sugar alcohols. By following the labeled carbon through metabolic processes, scientists can better understand the digestion, absorption, and utilization of sugar alcohols in the body. This research is important for developing dietary recommendations and therapeutic interventions for metabolic disorders.

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