Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013282 |
Molecular Formula: C4[13C]H12O5 |
Molecular Weight: 153.14 |
Chemical Structure |
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Description | Isotope labelled analogue of D-arabinitol, a sugar alcohol. D-arabinitol was used as a diagnostic tool for the detection of fungal infections in neutropenic patients. |
Synonyms | D-[1-13C]arabinitol; D-[1-13C]arabitol; D-[5-13C]lyxitol; D-arabinitol (1-13C); arabite (1-13C); D-arabinitol-1-13C |
Related CAS | 488-82-4 (unlabelled) |
Melting Point | 100-102°C |
Purity | 98% (CP); 98% atom 13C |
Solubility | Soluble in DMSO, Methanol |
Appearance | White to Off-White Solid |
Storage | Store at -20°C |
D-Arabinitol-[1-13C], a stable isotope-labeled compound, finds diverse applications in bioscience. Here are the key applications:
Metabolic Tracing: In the realm of metabolic studies, D-Arabinitol-[1-13C] emerges as a versatile tool for tracing the intricate pathways of carbohydrate metabolism. By integrating this labeled compound, researchers embark on a journey to meticulously monitor and quantify metabolic fluxes across various biological systems. This endeavor sheds light on the dynamic intricacies of sugar metabolism and its multifaceted regulation in diverse organisms, unraveling the mysteries of cellular energy processes.
Enzyme Mechanism Studies: At the core of enzyme mechanism investigations, D-Arabinitol-[1-13C] stands as a potent ally for unraveling the intricacies of enzymes engaged in carbohydrate metabolism. By leveraging this labeled substrate, researchers embark on a quest to pinpoint the intricate steps and intermediates involved in enzyme-catalyzed reactions. This wealth of information serves as a cornerstone for designing inhibitors or activators aimed at therapeutic interventions, paving the way for innovative treatments and precision medicine approaches.
Biochemical Research: Within the realm of biochemical exploration, D-Arabinitol-[1-13C] emerges as a linchpin for unraveling the roles of pentose sugars in cellular processes. The stable isotope labeling strategy opens doors to precise detection and quantification using cutting-edge techniques like mass spectrometry or nuclear magnetic resonance (NMR) spectroscopy. This analytical prowess facilitates in-depth delving into metabolic pathways, fostering the evolution of metabolic engineering strategies that hold the promise of transforming our understanding of cellular biochemistry.
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