D-glycerol-[1-13C]

D-glycerol-[1-13C], a stable isotope-labeled compound, plays a pivotal role in various research fields, tracing metabolic pathways and examining physiological processes. Here are the key applications of D-glycerol-[1-13C]:

Metabolic Flux Analysis: A cornerstone in metabolic research, D-glycerol-[1-13C] is a go-to tool for dissecting the intricate flow of carbon within metabolic pathways. By introducing this labeled compound into cellular systems, researchers gain a window into the distribution and metamorphosis of labeled carbon atoms. This technique is instrumental in unraveling the complexities of cellular metabolism and pinpointing pivotal control nodes in metabolic networks.

Enzyme Mechanism Studies: Delving into the realm of enzymology, D-glycerol-[1-13C] emerges as a key player in unraveling the mechanistic nuances of enzymatic reactions. Serving as a substrate for tracking the incorporation of the 13C label into intermediate and final reaction products, this compound is indispensable for deciphering enzyme kinetics and reaction mechanisms with a fine-tooth comb.

NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, D-glycerol-[1-13C] shines as a valuable asset for exploring molecular structures and dynamics with precision. The 13C label emits a distinctive magnetic resonance signal enabling precise tracking within the labyrinthine biological systems. Researchers leverage this labeled compound to delve into interactions, conformational shifts, and metabolic activities at the molecular level, unveiling the hidden intricacies of biological phenomena.

Biomedical Research: Within the realm of biomedical research, D-glycerol-[1-13C] finds its footing in exploring disease pathophysiology and metabolic changes in living organisms. By tracing this labeled compound in animal models, scientists gain profound insights into complex diseases like diabetes, cancer, and metabolic disorders. This knowledge serves as a springboard for identifying potential diagnostic markers and crafting therapeutic strategies anchored in metabolic profiling.