D-arabinose-[1,2-13C2]

D-arabinose-[1,2-13C2], an isotopically labeled sugar, holds diverse applications in bioscience research. Here are the key applications of D-arabinose-[1,2-13C2]:

Metabolic Flux Analysis: Utilizing D-arabinose-[1,2-13C2] in metabolic flux analysis allows researchers to trace complex metabolic pathways within cells. By examining the incorporation of labeled carbon atoms, insights into the intricate flow of carbon through diverse pathways can be revealed. This application is paramount for deciphering the nuances of cellular metabolism and refining strategies for metabolic engineering.

NMR Studies: The application of labeled D-arabinose in nuclear magnetic resonance (NMR) spectroscopy enables the detailed exploration of carbohydrate structure and dynamics, as well as their interactions with proteins. The presence of 13C atoms generates heightened signals in NMR, facilitating comprehensive structural elucidation. This capability is invaluable for drug development and enhancing comprehension of intricate carbohydrate-protein interactions in biological systems.

Quantitative Mass Spectrometry: D-arabinose-[1,2-13C2] serves as a crucial internal standard in quantitative mass spectrometry for precise quantification of D-arabinose levels in biological samples. This application aids in accurately measuring the intake and metabolism of this sugar under various physiological conditions, particularly in nutritional studies and investigations into metabolic disorders.

Tracer Studies in Microbial and Plant Systems: Within microbial and plant systems, the utilization of this isotopically labeled sugar in tracer experiments allows for in-depth exploration of carbon assimilation and utilization. By monitoring the labeled carbon, researchers can glean insights into the dynamics and regulation of specific metabolic pathways. This knowledge contributes significantly to advancements in biofuel production and the field of agricultural biotechnology.