Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013262 |
Molecular Formula: C3[13C]3H12O6 |
Molecular Weight: 183.13 |
Chemical Structure |
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Description | Labelled D-Galactose. A monosaccharide commonly occurring in milk sugar or lactose. |
Synonyms | D-[1,2,3-13C3]galactose; D-galactose-1,2,3-13C3 |
Related CAS | 59-23-4 (unlabelled) |
Boiling Point | 527.1 °C at 760 mmHg |
Melting Point | 150-152°C(lit.) |
Density | 1.581 g/cm3 |
D-Galactose-[1,2,3-13C3], a labeled sugar molecule with diverse research and medical applications, plays a crucial role in various fields. Here are the key applications:
Metabolic Pathway Tracing: Delving into metabolic pathways, D-Galactose-[1,2,3-13C3] is a cornerstone in studies aimed at unraveling the intricate processing of galactose within organisms. By monitoring the incorporation of labeled carbon atoms, scientists embark on a journey to dissect the complex web of galactose metabolism routes. This deep insight proves invaluable in deciphering disorders like galactosemia and fine-tuning efforts in metabolic engineering.
NMR Spectroscopy: Within the realm of nuclear magnetic resonance (NMR) spectroscopy, D-Galactose-[1,2,3-13C3] emerges as a vital probe, boasting the ability to enhance signal detection through its labeled carbons. This enhancement facilitates detailed structural and dynamic examinations of carbohydrates and their interplay. Researchers harness this wealth of information to probe the intricate structure-function relationships governing biomolecules, unlocking mysteries at the molecular level.
Glycoprotein Analysis: Serving as a linchpin in the analysis of glycoproteins, D-Galactose-[1,2,3-13C3] integrates itself into glycan structures, paving the way for a nuanced understanding of glycosylation patterns. This labeling strategy aids in mapping out intricate glycosylation networks and dissecting the pivotal roles of glycoproteins in cell signaling and disease pathways. Such investigations are pivotal in shaping the landscape of glycan-based therapies and diagnostic approaches, offering new avenues for medical intervention.
Pharmaceutical Research: In the dynamic realm of pharmaceutical research, D-Galactose-[1,2,3-13C3] takes center stage in the development and evaluation of novel drugs, particularly those targeting carbohydrate metabolism or recognition mechanisms. By leveraging the labeled sugar in pharmacokinetic studies, researchers illuminate the pathways of drug distribution and metabolic fate within the body. This comprehensive understanding forms the bedrock for assessing the efficacy and safety profiles of drug candidates, steering the course of pharmaceutical innovation towards optimized therapeutic outcomes.
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